对于患乳腺癌风险较高的女性，推荐的筛查时间和方式是什么？临床智讯。
What Are the Recommended Timing and Screening Modalities in Women at Higher Risk for Developing Breast Cancer? A Clin-IQ.
作者信息
Jatala Summer, Fitzgerald Shawn, Tietze Pamela, Ramakrishnan Kalyanakrishnan, McCarthy Laine H, Wickersham Elizabeth
机构信息
Family Medicine Residency Program, Department of Family and Preventive Medicine. University of Oklahoma Health Sciences Center, Oklahoma City, OK.
出版信息
J Patient Cent Res Rev. 2015 Winter;2(1):38-42. doi: 10.17294/2330-0698.1051. Epub 2015 Jan 30.
Early detection of breast cancer is desirable to prevent progression to advanced disease. This subject has been one of significant study and debate for women at normal risk, and recommendations continue to evolve. However, with regard to women at high risk, the recommendations from various health care professional organizations, including the recent recommendations from the United States Preventative Services Task Force, are different and also inconsistent concerning when to begin screening and which modalities should be used. We review several randomized controlled trials and consensus opinions regarding when to begin screening for breast cancer and how to best screen women at high risk. Specifically, we address women with known personal history of breast cancer, prior mantle radiation, or specific family history (including genetic family history) of breast cancer. The purpose of this inquiry is to present current evidence and suggest a clinical pathway regarding the screening of women at high risk for breast cancer.
早期发现乳腺癌对于预防疾病进展至晚期至关重要。对于处于正常风险的女性而言，这一主题一直是大量研究和讨论的焦点，相关建议也在不断演变。然而，对于高危女性，包括美国预防服务工作组近期建议在内的各类医疗专业组织的建议，在何时开始筛查以及应采用何种筛查方式方面存在差异且并不一致。我们回顾了多项关于何时开始乳腺癌筛查以及如何对高危女性进行最佳筛查的随机对照试验和共识意见。具体而言，我们探讨了有乳腺癌个人病史、既往接受过斗篷野放疗或有乳腺癌特定家族史（包括遗传家族史）的女性。本次探究的目的是呈现当前证据，并就高危乳腺癌女性的筛查提出临床路径建议。
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