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[使用自动持续气道正压通气治疗对睡眠呼吸暂停低通气综合征患者进行高级事件检测的验证]

[Validation of the advanced event detection in patients with sleep apnea hypopnea syndrome using auto-CPAP treatment].

作者信息

Zhou Wei, Dong Xiaosong, Li Jing, Zhao Long, An Pei, Han Fang

机构信息

Department of Respiratory Medicine and Intensive Care Unit.Peking University People's Hospital, Beijing 100044, China.

Department of Respiratory Medicine and Intensive Care Unit.Peking University People's Hospital, Beijing 100044, China; Email:

出版信息

Zhonghua Jie He He Hu Xi Za Zhi. 2015 Nov;38(11):844-7.

Abstract

OBJECTIVE

To validate the use of the event detection capabilities in an auto-CPAP system used by patients with sleep apnea hypopnea syndrome (SAHS).

METHODS

A total of 28 subjects with SAHS were recruited in the study. All the underwent tests of polysomnography (PSG) before and during treatment by an-auto-CPAP system with advanced event detection (AED) in the sleep lab. Apnea-hypopnea index (AHI), apnea index (AI) and hypopnea index (HI) by PSG and PAP machine were compared.

RESULTS

The mean AHI derived from PSG and AED was (6.1 ± 5.6) and (7.1 ± 5.3) times/h (P>0.05), AI was (5.4 ± 5.4) and (4.6 ± 4.2) times/h (P>0.05), HI was (0.77 ± 1.07) and (2.54 ± 1.98) times/h (P<0.05). The Spearman correlation coefficient of AHI was 0.698 (P<0.05), AI was 0.767 (P<0.05), HI was 0.141 (P>0.05). Bland-Altman plot also showed a high agreement between AHI derived from PSG and AHI derived from AED.

CONCLUSION

AED showed a high agreement with PSG in the detection of AHI and AI, but not in HI. This technique may be helpful to monitor the efficacy of PAP treatment at home for long-term follow-up.

摘要

目的

验证自动持续气道正压通气(auto-CPAP)系统中事件检测功能在睡眠呼吸暂停低通气综合征(SAHS)患者中的应用效果。

方法

本研究共招募了28例SAHS患者。所有患者在睡眠实验室接受了多导睡眠图(PSG)检查,以及使用具有高级事件检测(AED)功能的auto-CPAP系统进行治疗前后的检查。比较了PSG和PAP机器得出的呼吸暂停低通气指数(AHI)、呼吸暂停指数(AI)和低通气指数(HI)。

结果

PSG和AED得出的平均AHI分别为(6.1±5.6)次/小时和(7.1±5.3)次/小时(P>0.05),AI分别为(5.4±5.4)次/小时和(4.6±4.2)次/小时(P>0.05),HI分别为(0.77±1.07)次/小时和(2.54±1.98)次/小时(P<0.05)。AHI的Spearman相关系数为0.698(P<0.05),AI为0.767(P<0.05),HI为0.141(P>0.05)。Bland-Altman图也显示PSG得出的AHI与AED得出的AHI之间具有高度一致性。

结论

AED在检测AHI和AI方面与PSG具有高度一致性,但在检测HI方面并非如此。该技术可能有助于在家中监测PAP治疗的疗效,以便进行长期随访。

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