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基于 DNA 的癌症精准医疗:过度兴奋的案例?

DNA-Guided Precision Medicine for Cancer: A Case of Irrational Exuberance?

机构信息

Division of Medical Oncology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.

Division of Molecular Carcinogenesis, The Netherlands Cancer Institute, Amsterdam, the Netherlands.

出版信息

Cancer Discov. 2016 Feb;6(2):130-2. doi: 10.1158/2159-8290.CD-15-1321.

Abstract

Precision treatment with targeted cancer drugs requires the selection of patients who are most likely to benefit from a given therapy. We argue here that the use of a combination of both DNA and transcriptome analyses will significantly improve drug response prediction.

摘要

精准治疗需要选择最有可能从特定疗法中获益的患者。在这里,我们认为同时使用 DNA 和转录组分析将显著提高药物反应预测的准确性。

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