Stowkowy Jacqueline, Liu Lu, Cadenhead Kristin S, Cannon Tyrone D, Cornblatt Barbara A, McGlashan Thomas H, Perkins Diana O, Seidman Larry J, Tsuang Ming T, Walker Elaine F, Woods Scott W, Bearden Carrie E, Mathalon Daniel H, Addington Jean
Department of Psychiatry, Mathison Centre for Mental Health Research and Education, University of Calgary, 3280 Hospital Drive NW, Calgary, AB, T2N 4Z6, Canada.
Department of Psychiatry, UCSD, La Jolla, CA, USA.
Soc Psychiatry Psychiatr Epidemiol. 2016 Apr;51(4):497-503. doi: 10.1007/s00127-016-1182-y. Epub 2016 Feb 6.
There is evidence to suggest that both early traumatic experiences and perceived discrimination are associated with later onset of psychosis. Less is known about the impact these two factors may have on conversion to psychosis in those who are at clinical high risk (CHR) of developing psychosis. The purpose of this study was to determine if trauma and perceived discrimination were predictors of conversion to psychosis.
The sample consisted of 764 individuals who were at CHR of developing psychosis and 280 healthy controls. All participants were assessed on past trauma, bullying and perceived discrimination.
Individuals at CHR reported significantly more trauma, bullying and perceived discrimination than healthy controls. Only perceived discrimination was a predictor of later conversion to psychosis.
Given that CHR individuals are reporting increased rates of trauma and perceived discrimination, these should be routinely assessed, with the possibility of offering interventions aimed at ameliorating the impact of past traumas as well as improving self-esteem and coping strategies in an attempt to reduce perceived discrimination.
有证据表明,早期创伤经历和感知到的歧视都与精神病的后期发作有关。对于这两个因素对处于临床高风险(CHR)发展为精神病的人群转化为精神病可能产生的影响,人们了解较少。本研究的目的是确定创伤和感知到的歧视是否是转化为精神病的预测因素。
样本包括764名处于发展为精神病临床高风险的个体和280名健康对照者。所有参与者都接受了关于过去创伤、欺凌和感知到的歧视的评估。
与健康对照者相比,处于临床高风险的个体报告的创伤、欺凌和感知到的歧视明显更多。只有感知到的歧视是后期转化为精神病的预测因素。
鉴于处于临床高风险的个体报告的创伤和感知到的歧视发生率有所增加,应该对这些情况进行常规评估,并有可能提供干预措施,旨在减轻过去创伤的影响,同时提高自尊和应对策略,以试图减少感知到的歧视。