Vrzhesinskaya O A, Kodentsova V M, Pereverzeva O G, Gmoshinskaya M V, Pustograev N N
Vopr Pitan. 2015;84(4):105-11.
With the help of non-invasive methods the sufficiency with vitamins C, B1 and B2 in 58 newborns (38-40 weeks of gestation) on breastfeeding as well as on mixed or artificial feeding has been evaluated. Urinary excretion and breast content of ascorbic acid (measured by visual titration), thiamin (by thiochrome fluorimetric method) andriboflavin (fluorimetrically by titration with riboflavin-binding protein) was determined on the 3-10th day after birth. 35 infants were exclusively breastfed. 40% of their mothers regularly took multivitamin supplements during pregnancy and 42.9%--both during pregnancy and after childbirth, 17.1% did not use vitamin complexes either duringpregnancy or after childbearing. The content of vitamins C, B1 and B2 in the breast milk of women who did not additionally intake vitamins during pregnancy and lactation, was reduced compared with that of mothers who took multivitamin supplements, and provided only a half of the needs of their child in these vitamins. All these babies have urinary excretion of vitamins below the lower limit of norm. Among infants whose mothers took multivitamin supplements during pregnancy, but stop taking them immediately after their birth, only 28.6% of newborns were provided with vitamin C, while all the children identified a lack of vitamins By and B2. The insufficiency with vitamins C and B1 was detected in one third of children breastfed by mothers who took vitamins during pregnancy and continued intaking them after birth, adequate supplied with vitamin B2 was 35.7% of the surveyed. Determination of vitamin urinary excretion (perg creatinine) is useful for vitamin status evaluation. The content of vitamins in breast milk can be used for assessment of vitamin status both a nursing woman and her child. Taking into consideration that the diet of a breastfeeding woman is not always the best, there is no doubt about the need to continue multivitamin intake during breastfeeding. The question on the doses of vitamins in vitamin-mineral supplements for lactating women, providing vitamin content of breast milk at an optimal level, or intended specifically for infants, nowadays is extensively discussed.
借助非侵入性方法,对58名(妊娠38 - 40周)采用母乳喂养、混合喂养或人工喂养的新生儿体内维生素C、B1和B2的充足情况进行了评估。在出生后第3 - 10天测定了尿中抗坏血酸(通过目视滴定法测定)、硫胺素(硫色素荧光法)和核黄素(用核黄素结合蛋白荧光滴定法)的排泄量以及母乳中的含量。35名婴儿为纯母乳喂养。其母亲中40%在孕期定期服用多种维生素补充剂,42.9%在孕期和产后都服用,17.1%在孕期或产后都未使用维生素复合物。在孕期和哺乳期未额外摄入维生素的女性母乳中,维生素C、B1和B2的含量与服用多种维生素补充剂的母亲相比有所降低,仅能满足其孩子对这些维生素需求的一半。所有这些婴儿尿中维生素的排泄量均低于正常下限。在母亲孕期服用多种维生素补充剂但产后立即停止服用的婴儿中,只有28.6%的新生儿维生素C充足,而所有儿童都存在维生素B1和B2缺乏的情况。在母亲孕期服用维生素且产后继续服用的母乳喂养儿童中,三分之一检测出维生素C和B1不足,维生素B2供应充足的占被调查者的35.7%。测定尿中维生素排泄量(每克肌酐)有助于评估维生素状态。母乳中维生素的含量可用于评估哺乳期妇女及其孩子的维生素状态。考虑到哺乳期妇女的饮食并不总是最佳的,毫无疑问在哺乳期需要继续摄入多种维生素。如今,关于哺乳期妇女维生素 - 矿物质补充剂中维生素剂量的问题,即如何使母乳中的维生素含量达到最佳水平或专门针对婴儿的剂量,正在广泛讨论。