van de Borne Philippe, Missault Luc, Persu Alexandre, Van Mieghem Walter
Acta Cardiol. 2016 Feb;71(1):35-40. doi: 10.2143/AC.71.1.3132095.
The aim of this study was to assess hypertension management in general practice in Belgium and Luxembourg, shortly before the publication of the 2013 ESH/ESC Guidelines for arterial hypertension management.
A total of 516 general physicians evaluated 10,078 consecutive hypertensive patients. All used the same definitions to assess cardiovascular risk.
Systolic (S) blood pressure (BP) was 139 ± 19 mmHg, diastolic (D) BP 80 ± 11 mmHg, patients were 64 ± 13 years old and their body mass index (BMI) was 28 ± 5 kg/m2 (mean ± SD). Treatment remained unchanged in 71% of the patients with a SBP ≥ 140 mmHg. Those on ≥ 2 antihypertensive drugs were older, had higher BMI, slower HR, higher perceived cardiovascular risk, but lower BP (all P ≤ 0.001 vs no and monotherapy groups). Patients in whom treatment was intensified were at higher cardiovascular risk, as substantiated by an increased prevalence of males, a higher BP, a faster HR and a larger BMI (all P ≤ 0.0001). High cardiovascular risk patients underwent more frequent treatment simplifications with fixed-combination therapies or the addition of another antihypertensive class (all P ≤ 0.0001 vs not at high cardiovascular risk). Among the 523 patients older than 80 years with SBP ≥ 140 mmHg, treatment intensification occurred in 32% when SBP ≥ 150 mmHg, and in 10% when SBP was between 140 and 149 mmHg (P ≤ 0.0001).
The COME STAI study suggests that there is still room for improvement in hypertension control in Belgium and Luxembourg.
本研究旨在评估在2013年欧洲高血压学会(ESH)/欧洲心脏病学会(ESC)动脉高血压管理指南发布前不久,比利时和卢森堡全科医疗中高血压的管理情况。
共有516名全科医生对10078例连续性高血压患者进行了评估。所有人都使用相同的定义来评估心血管风险。
收缩压(SBP)为139±19 mmHg,舒张压(DBP)为80±11 mmHg,患者年龄为64±13岁,体重指数(BMI)为28±5 kg/m²(均值±标准差)。在收缩压≥140 mmHg的患者中,71%的患者治疗方案未改变。服用≥2种降压药物的患者年龄更大、BMI更高、心率更慢、感知到的心血管风险更高,但血压更低(与未治疗组和单药治疗组相比,所有P≤0.001)。治疗强化的患者心血管风险更高,表现为男性患病率增加、血压更高、心率更快和BMI更大(所有P≤0.0001)。高心血管风险患者更频繁地采用固定复方疗法简化治疗或加用另一类降压药物(与非高心血管风险患者相比,所有P≤0.0001)。在523例年龄≥80岁且收缩压≥140 mmHg的患者中,收缩压≥150 mmHg时治疗强化发生率为32%,收缩压在140至149 mmHg之间时为10%(P≤0.0001)。
COME STAI研究表明,比利时和卢森堡在高血压控制方面仍有改进空间。