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[老年疗养院居民的动脉高血压、抗高血压治疗及就诊间血压变异性]

[Arterial hypertension, antihypertensive therapy, and visit-to-visit blood pressure variability of elderly nursing home residents].

作者信息

Könner F, Kuhnert R, Budnick A, Kolloch R, Scholze J, Dräger D, Kreutz R

机构信息

Institut für Klinische Pharmakologie und Toxikologie, Charité - Universitätsmedizin Berlin.

Institut für Medizinische Soziologie und Rehabilitationswissenschaft, Charité - Universitätsmedizin Berlin.

出版信息

Dtsch Med Wochenschr. 2014 Nov;139(48):2441-7. doi: 10.1055/s-0034-1387422. Epub 2014 Nov 19.

Abstract

BACKGROUND AND AIM

Arterial hypertension is a common health problem in older nursing home residents (NHR). The aim of this study was to prospectively analyze blood pressure (BP) patterns, antihypertensive therapy, and visit-to-visit BP variability in NHR.

METHODS

BP, visit-to-visit variability (estimated by standard deviation of means) of systolic BP (SBP) were analyzed in 12 nursing homes in Germany. NHR who were at least 65 years old and had no moderate or severe dementia were studied at baseline (T0), after 3 and 6 months, respectively.

RESULTS

BP data were available for 177 NHR (mean age 83.8, 69.5% female) at T0.  A total of 90.4% NHR was affected by hypertension. Mean systolic/diastolic blood pressure was 130,1/75,5 mmHg. BP values of ≥ 140/90 mmHg were found in 29.9%, while 33.9% of NHR exhibited SBP values < 120 mmHg. At least one antihypertensive drug was used in 84.2%, and 40.7% of NHR were treated with at least three different drugs. The median of the visit-to-visit SBP variability was 9.05 (Min. 0, Max. 35.78); an influence of age, sex, and type of antihypertensive medication was not found.

CONCLUSION

Elderly German NHR showed a high prevalence of hypertension and BP was controlled in 80%. However, a large proportion received intensive BP lowering pharmacotherapy and exhibited SBP values clearly lower than recommend target values between 140 and 150 mmHg particularly for elderly patients over 80 years. Thus, to avoid overtreatment BP should be monitored closely to adapt antihypertensive therapy in this population.

摘要

背景与目的

动脉高血压是老年疗养院居民(NHR)中常见的健康问题。本研究旨在对NHR的血压模式、抗高血压治疗以及每次就诊间的血压变异性进行前瞻性分析。

方法

在德国的12家疗养院中对收缩压(SBP)的血压及每次就诊间的变异性(通过均值标准差估算)进行分析。对年龄至少65岁且无中度或重度痴呆的NHR在基线期(T0)、3个月后和6个月后分别进行研究。

结果

在T0期,177名NHR(平均年龄83.8岁,69.5%为女性)有血压数据。总计90.4%的NHR患有高血压。平均收缩压/舒张压为130.1/75.5mmHg。血压值≥140/90mmHg的占29.9%,而33.9%的NHR收缩压值<120mmHg。84.2%的患者使用了至少一种抗高血压药物,40.7%的NHR接受了至少三种不同药物的治疗。每次就诊间SBP变异性的中位数为9.05(最小值0,最大值35.78);未发现年龄、性别和抗高血压药物类型的影响。

结论

德国老年NHR高血压患病率高,80%的血压得到控制。然而,很大一部分患者接受了强化降压药物治疗,尤其是80岁以上的老年患者,其收缩压值明显低于140至150mmHg的推荐目标值。因此,为避免过度治疗,应密切监测该人群的血压以调整抗高血压治疗。

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