Prakruthi B V, Babu N C
Department of Oral and Maxillofacial Pathology, The Oxford Dental College, Hospital and Research Centre, Bommanahalli, Bangalore, Karnataka, India.
Indian J Cancer. 2015 Apr-Jun;52(2):232-4. doi: 10.4103/0019-509X.175844.
Circulating tumor cells (CTCs) are those cells present in the blood and have antigenic and/or genetic characteristics of a specific tumor type. CTCs can be detected in the peripheral blood of cancer patients. Various techniques are available for detection of CTCs, which provide evidence for future metastasis. CTCs may provide new insight into the biology of cancer and process of metastasis in oral squamous cell carcinoma (OSCC). The detection of CTCs may represent a new diagnostic tool for predicting the occurrence of metastatic disease in OSCC and endow with the treatment strategies to efficiently treat and prevent cancer metastasis. This review gives an insight into the significance of CTCs and different techniques for detection of CTCs.
循环肿瘤细胞（CTCs）是存在于血液中且具有特定肿瘤类型抗原性和/或基因特征的细胞。癌症患者的外周血中可检测到循环肿瘤细胞。有多种技术可用于检测循环肿瘤细胞，这些技术为未来的转移提供了证据。循环肿瘤细胞可能为口腔鳞状细胞癌（OSCC）的癌症生物学和转移过程提供新的见解。循环肿瘤细胞的检测可能代表一种预测OSCC转移疾病发生的新诊断工具，并为有效治疗和预防癌症转移提供治疗策略。本综述深入探讨了循环肿瘤细胞的重要性以及检测循环肿瘤细胞的不同技术。
