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复杂康复与类风湿性关节炎在职患者的临床状况:冷冻疗法是否总是优于传统康复?

Complex rehabilitation and the clinical condition of working rheumatoid arthritis patients: does cryotherapy always overtop traditional rehabilitation?

作者信息

Księżopolska-Orłowska Krystyna, Pacholec Anna, Jędryka-Góral Anna, Bugajska Joanna, Sadura-Sieklucka Teresa, Kowalik Katarzyna, Pawłowska-Cyprysiak Karolina, Łastowiecka-Moras Elżbieta

机构信息

a Department of Rehabilitation and.

b Department of Education , Institute of Rheumatology , Warsaw , Poland , and.

出版信息

Disabil Rehabil. 2016;38(11):1034-40. doi: 10.3109/09638288.2015.1060265. Epub 2016 Feb 6.

DOI:10.3109/09638288.2015.1060265
PMID:26853597
Abstract

AIM

Rehabilitation slows the progress of rheumatoid arthritis (RA) and prevents progression of disability. This study aimed to compare the impact of two rehabilitation programmes on pain, disease activity, locomotor function, global health and work ability forecast in RA patients.

MATERIALS AND METHODS

Sixty-four employed women aged 24-65 years participated in the study. All patients underwent individual and instrumental kinesiotherapy. Thirty-two patients underwent cryogenic chamber therapy and local cryotherapy as well as non-weight-bearing, instrumental and individual kinesiotherapy. The remaining 32 patients received traditional rehabilitation in the form of electromagnetic and instrumental therapy, individual and pool-based non-weight-bearing kinesiotherapy. Rehabilitation lasted 3 weeks. Patients were examined three times: prior to rehabilitation, after 3 weeks of therapy and 3 months after completion of rehabilitation. The following study instruments were used: to assess disease activity: DAS-28; functional impairment: HAQ-DI; pain severity: VAS; patients' overall well-being: a scale from 0 to 100 (Global Health Index); and patients' own prognosis of fitness for work: the 6th question from Work Ability Index (WAI). Statistical analysis of data was performed using the STATISTICA 8.0 package. Mixed-design two-way analysis of variance was used for hypothesis testing.

RESULTS

All patients improved after rehabilitation. The group of patients those who underwent cryotherapy had improved DAS-28, HAQ-DI, VAS and global health scores immediately following the 3-week rehabilitation programme (p < 0.001, p = 0.001, p = 0.007 and p < 0.001, respectively), as well as at the 3-month follow-up (p < 0.001, p < 0.001, p = 0.009 and p < 0.001, respectively). Rehabilitation using cryotherapy resulted in greater improvement in disease activity DAS-28 [F(2,105) = 5.700; p = 0.007; η(2) = 0.084] and HAQ-DI locomotor function scores [F(2,109) = 6.771; p = 0.003; η(2) = 0.098] compared to traditional rehabilitation. The impact of both forms of rehabilitation on patients' own prognosis of work ability in the next 2 years was not significant. Results of patients who underwent traditional approach showed decreased disease activity following the initial 3-week period; however, this improvement did not sustain to the end of follow-up, 3 months later.

CONCLUSIONS

Complex rehabilitation in RA has a positive effect on patients' clinical condition. The rehabilitation programme that includes cryotherapy overtops traditional rehabilitation, particularly as regards improvement in locomotor function, disease activity and sustaining willingness to continue working and exerts long-lasting effect.

IMPLICATIONS FOR REHABILITATION

Rehabilitation using cryotherapy is more effective in improving locomotor function, decreasing disease activity and sustaining willingness to continue working compared to traditional rehabilitation. Rehabilitation using cryotherapy significantly reduces the intensity of pain experienced by patients with RA, and this positive effect is maintained at 3 months post-rehabilitation. Complex rehabilitation, particularly treatment using cryotherapy, improves patients' subjective assessment of their overall well-being and perception of their disease. Complex rehabilitation in rheumatoid arthritis has a positive effect on patients' clinical condition.

摘要

目的

康复治疗可减缓类风湿关节炎(RA)的病情发展并防止残疾进展。本研究旨在比较两种康复方案对RA患者疼痛、疾病活动度、运动功能、整体健康状况及工作能力预测的影响。

材料与方法

64名年龄在24至65岁之间的在职女性参与了本研究。所有患者均接受了个体化和器械运动疗法。32名患者接受了低温舱疗法和局部冷冻疗法以及非负重、器械和个体化运动疗法。其余32名患者接受了以电磁和器械疗法、个体化和基于泳池的非负重运动疗法形式的传统康复治疗。康复治疗持续3周。患者接受了三次检查:康复治疗前、治疗3周后以及康复治疗完成后3个月。使用了以下研究工具:评估疾病活动度:DAS-28;功能损害:HAQ-DI;疼痛严重程度:VAS;患者总体幸福感:0至100分制(全球健康指数);以及患者自身的工作适应预后:工作能力指数(WAI)的第6个问题。使用STATISTICA 8.0软件包对数据进行统计分析。采用混合设计双向方差分析进行假设检验。

结果

所有患者康复后均有改善。接受冷冻疗法的患者组在为期3周的康复方案结束后,DAS-28、HAQ-DI、VAS和全球健康评分立即得到改善(分别为p < 0.001、p = 0.001、p = 0.007和p < 0.001),在3个月随访时也有改善(分别为p < 0.001、p < 0.001、p = 0.009和p < 0.001)。与传统康复治疗相比,使用冷冻疗法进行康复治疗在疾病活动度DAS-28 [F(2,105) = 5.700;p = 0.007;η(2) = 0.084]和HAQ-DI运动功能评分[F(2,109) = 6.771;p = 0.003;η(2) = 0.098]方面带来了更大的改善。两种康复形式对患者未来2年工作能力自身预后的影响均不显著。接受传统方法治疗的患者在最初3周后疾病活动度有所下降;然而,这种改善在3个月后的随访结束时并未持续。

结论

RA的综合康复治疗对患者的临床状况有积极影响。包括冷冻疗法的康复方案优于传统康复治疗,特别是在改善运动功能、疾病活动度以及维持继续工作的意愿方面,并具有持久的效果。

对康复治疗的启示

与传统康复治疗相比,使用冷冻疗法进行康复治疗在改善运动功能、降低疾病活动度以及维持继续工作的意愿方面更有效。使用冷冻疗法进行康复治疗可显著降低RA患者所经历疼痛的强度,且这种积极效果在康复治疗后3个月仍得以维持。综合康复治疗,特别是使用冷冻疗法的治疗,可改善患者对其总体幸福感的主观评估及其对疾病的认知。类风湿关节炎的综合康复治疗对患者的临床状况有积极影响。

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