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微小土壤杆菌属中一个物种的首个完整基因组序列,一种从锡金喜马拉雅地区分离出的嗜极产冷活性酶细菌菌株ERGS5:02。

First complete genome sequence of a species in the genus Microterricola, an extremophilic cold active enzyme producing bacterial strain ERGS5:02 isolated from Sikkim Himalaya.

作者信息

Swarnkar Mohit Kumar, Singh Dharam, Kumar Rakshak

机构信息

Department of Biotechnology, CSIR-Institute of Himalayan Bioresource Technology, Post Box No. 06, Palampur 176 061, Himachal Pradesh, India.

Department of Biotechnology, CSIR-Institute of Himalayan Bioresource Technology, Post Box No. 06, Palampur 176 061, Himachal Pradesh, India.

出版信息

J Biotechnol. 2016 Mar 20;222:17-8. doi: 10.1016/j.jbiotec.2016.02.011. Epub 2016 Feb 6.

Abstract

Here, we report the first ever complete genome sequence of any species in the genus Microterricola. The bacterium Microterricola viridarii ERGS5:02 isolated from the glacial stream of Sikkim Himalaya survived at low temperature and exhibited enhanced growth upon UV treatment, in addition, it also produced cold active enzymes. The complete genome assembly of 3.7 Mb suggested for the presence of genetic elements favoring the survival of bacterium under extreme conditions of UV and low temperature besides producing amylase, lipase and protease of industrial relevance.

摘要

在此,我们报告了微土栖菌属中任何物种的首个完整基因组序列。从锡金喜马拉雅山冰川溪流中分离出的微土栖绿菌ERGS5:02能够在低温下存活,经紫外线处理后生长增强,此外,它还能产生冷活性酶。3.7 Mb的完整基因组组装表明,除了产生具有工业相关性的淀粉酶、脂肪酶和蛋白酶外,还存在有利于该细菌在紫外线和低温等极端条件下生存的遗传元件。

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