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[克雅氏综合征的临床诊断——6例病例分析]

[Clinical diagnosis of Jakob-Creutzfeldt syndrome--analysis of 6 cases].

作者信息

Honczarenko K, Kulczycki J, Fryze C, Nowacki P, Stroińska-Kuś B, Matyjek J, Korwin-Piotrowska T, Tarnowska-Dziduszko E, Iwińska B

机构信息

Z Pracowni Neuropatologii Kliniki Neurologii PAM w Szczecinie, Instytutu Psychiatrii i Neurologii w Warszawie.

出版信息

Neurol Neurochir Pol. 1989 Jan;23(1):1-6.

PMID:2685628
Abstract

The authors present an analysis of the clinical course of 6 cases of Creutzfeldt-Jakob disease (patients were aged from 27 to 59 years). The diagnosis was established during the life of the patients. In the neurological status dementia and syndromes of pyramidal and extrapyramidal lesions predominated. Neuropathological examinations in 5 cases demonstrated also considerable cerebellar damage, however, clinical signs of this damage were noted in two patients only. EEG findings were of greatest importance among the laboratory investigations.

摘要

作者对6例克雅氏病患者(年龄在27至59岁之间)的临床病程进行了分析。诊断是在患者生前确立的。神经学状态方面,痴呆以及锥体和锥体外系病变综合征最为突出。5例患者的神经病理学检查还显示小脑有相当程度的损害,然而,只有两名患者出现了这种损害的临床体征。在实验室检查中,脑电图结果最为重要。

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