Monabati Ahmad, Safavi Moeinadin, Solhjoo Freidoon
Department of Pathology, Molecular Pathology and Cytogenetic Unit, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
J Gastrointest Surg. 2016 Jun;20(6):1275-7. doi: 10.1007/s11605-016-3098-y. Epub 2016 Feb 8.
Extragastrointestinal stromal tumors (EGIST) are rarer counterparts of gastrointestinal stromal tumors (GIST) in omentum, mesentery, and retroperitoneum.
Hereby, authors present a 47-year-old man with abdominal mass whose abdominal CT scan revealed a large septated cystic mass measuring 16 cm in largest diameter. The mass was aspirated and resected by laparotomy. Pathologic examination exhibited a mesenchymal spindle cell neoplasm which was immunohistochemically reactive for CD117 and SMA. Thus, the diagnosis of extragastrointestinal stromal tumor was made.
A cystic EGIST in omentum falls in the differential diagnoses of omental cystic lesions which include omental cyst, mesenteric teratoma, cystic mesothelioma, cystic spindle cell tumors, pseudomyxoma peritonei, pancreatic pseudocyst, and complicated ascites. Therefore, proper diagnosis of cystic GIST is of great importance in respect to different behavior, management, and complications in comparison to its mimickers and GI counterparts.
胃肠道外间质瘤(EGIST)是胃肠道间质瘤(GIST)在大网膜、肠系膜和腹膜后的罕见对应物。
在此,作者介绍了一名47岁的腹部肿块男性患者,其腹部CT扫描显示一个最大直径为16厘米的大的分隔囊性肿块。通过剖腹手术对该肿块进行了抽吸和切除。病理检查显示为间叶性梭形细胞瘤,免疫组化对CD117和SMA呈阳性反应。因此,诊断为胃肠道外间质瘤。
大网膜中的囊性EGIST属于大网膜囊性病变的鉴别诊断范围,包括大网膜囊肿、肠系膜畸胎瘤、囊性间皮瘤、囊性梭形细胞瘤、腹膜假黏液瘤、胰腺假性囊肿和复杂性腹水。因此,与模仿者和胃肠道对应物相比,正确诊断囊性GIST对于其不同的行为、管理和并发症非常重要。