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Ann Med Surg (Lond). 2015 Nov 25;5:35-7. doi: 10.1016/j.amsu.2015.11.009. eCollection 2016 Feb.
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A case of multiple endocrine neoplasia: hyperparathyroidism, insulinoma, GRF-oma, hypercalcitoninaemia and intractable peptic ulceration.一例多发性内分泌腺瘤病：甲状旁腺功能亢进、胰岛素瘤、生长激素释放因子瘤、高降钙素血症及难治性消化性溃疡。
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本文引用的文献

1
Multiple endocrine neoplasia type 2.多发性内分泌腺瘤病 2 型。
Front Horm Res. 2013;41:16-29. doi: 10.1159/000345667. Epub 2013 Mar 19.
2
Calcium-sensing receptor is a physiologic multimodal chemosensor regulating gastric G-cell growth and gastrin secretion.钙敏感受体是一种生理多模式化学感受器，调节胃 G 细胞的生长和胃泌素的分泌。
Proc Natl Acad Sci U S A. 2010 Oct 12;107(41):17791-6. doi: 10.1073/pnas.1009078107. Epub 2010 Sep 27.
3
Genotype-phenotype relationship in multiple endocrine neoplasia type 2. Implications for clinical management.2型多发性内分泌腺瘤病的基因型-表型关系。对临床管理的启示。
Hormones (Athens). 2009 Jan-Mar;8(1):23-8. doi: 10.14310/horm.2002.1218.
4
Somatostatin and its analogues in peptic ulcer bleeding: facts and pathophysiological aspects.生长抑素及其类似物在消化性溃疡出血中的应用：事实与病理生理学方面
Dig Liver Dis. 2006 Feb;38(2):143-8. doi: 10.1016/j.dld.2005.05.009. Epub 2005 Jul 7.
5
The phenotypes associated with ret mutations in the multiple endocrine neoplasia type 2 syndrome.与2型多发性内分泌腺瘤综合征中ret基因突变相关的表型。
Cancer Res. 1999 Apr 1;59(7 Suppl):1736s-1741s; discussion 1742s.
6
Medullary thyroid carcinoma in multiple endocrine neoplasia types 2A and 2B.2A和2B型多发性内分泌腺瘤病中的甲状腺髓样癌。
Surgery. 1994 Dec;116(6):1017-23.
7
Primary hyperparathyroidism in multiple endocrine neoplasia type 2A.2A 型多发性内分泌腺瘤病中的原发性甲状旁腺功能亢进症
J Intern Med. 1995 Oct;238(4):369-73. doi: 10.1111/j.1365-2796.1995.tb01212.x.
8
Multiple endocrine neoplasia type 2B: more than an endocrine disorder.2B型多发性内分泌腺瘤病：不止是一种内分泌紊乱疾病。
Surgery. 1995 Dec;118(6):936-42. doi: 10.1016/s0039-6060(05)80097-2.
9
Correct preoperative localization: does it permit a change in operative strategy for primary hyperparathyroidism?
Surgery. 1995 Dec;118(6):932-5. doi: 10.1016/s0039-6060(05)80096-0.
10
Primary hyperparathyroidism: changes in the pattern of clinical presentation.原发性甲状旁腺功能亢进症：临床表现模式的变化
Lancet. 1980 Jun 21;1(8182):1317-20. doi: 10.1016/s0140-6736(80)91783-3.

2A型多发性内分泌腺瘤病（MEN）综合征的罕见表现。

A rare presentation of multiple endocrine neoplasia (MEN) type 2A syndrome.

作者信息

Weledji Elroy Patrick

机构信息

Department of Surgery, Faculty of Health Sciences, University of Buea, PO Box 126, Limbe S.W. Region, Buea, Cameroon.

出版信息

Ann Med Surg (Lond). 2015 Nov 25;5:35-7. doi: 10.1016/j.amsu.2015.11.009. eCollection 2016 Feb.

DOI:10.1016/j.amsu.2015.11.009
PMID:26858832
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4706555/
Abstract

Peptic ulcer disease may be a manifestation of symptomatic primary hyperparathyroidism. A case of an intractable complicated peptic ulcer disease secondary to hypercalcaemia from multiple endocrine neoplasia type 2A is presented. Hypercalcaemia should always be excluded as a cause of recurrent, or complicated peptic ulcer disease.

摘要

消化性溃疡病可能是症状性原发性甲状旁腺功能亢进的一种表现。本文报告一例由2A型多发性内分泌肿瘤引起高钙血症继发的顽固性复杂性消化性溃疡病。高钙血症作为复发性或复杂性消化性溃疡病的病因应始终被排除。