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厌氧菌感染的抗生素治疗

Antibiotic treatment of anaerobic infections.

作者信息

Panichi G

机构信息

Department of Infectious Diseases, University of Sassari, Italy.

出版信息

Scand J Infect Dis Suppl. 1989;62:47-51.

PMID:2685992
Abstract

Many bacterial infections, for example those in chest and abdomen, intracranial infections and infections in the female genital tract have anaerobic or mixed aerobic/anaerobic aetiology. Recent data indicate that anaerobes, alone or together with aerobes, are found in 15% to 30% of all positive bacteriological cultures. In 1988 at our laboratory, 284 (75%) of 379 positive cultures yielded aerobes only, 23 (6%) anaerobes only and 72 (19%) mixed aerobes and anaerobes. The initial choice of antibiotics in infections known or suspected to involve anaerobes should be based on the site of the infection, the anticipated aetiology and the severity of the infection. The place in therapy of antibiotics active against anaerobes is discussed.

摘要

许多细菌感染,例如胸部和腹部感染、颅内感染以及女性生殖道感染,都具有厌氧或需氧/厌氧混合的病因。最新数据表明,在所有阳性细菌培养物中,15%至30%可发现厌氧菌,单独或与需氧菌共同存在。1988年在我们实验室,379份阳性培养物中,284份(75%)仅培养出需氧菌,23份(6%)仅培养出厌氧菌,72份(19%)培养出需氧菌和厌氧菌的混合物。对于已知或怀疑涉及厌氧菌的感染,抗生素的初始选择应基于感染部位、预期病因和感染严重程度。本文讨论了抗厌氧菌抗生素在治疗中的地位。

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