Biologic response modifiers in cancer therapy: a review.

Biologic response modifiers have expanded the therapeutic horizon of medical oncology. These agents, procedures, and interventions are likely to become an established fourth modality of cancer therapy in the near future. This is a succinct review of the most prominent areas of clinical research and the results obtained, including cytokines (interferons, interleukins), growth factors, monoclonal antibodies, adoptive immunotherapy, and tumor vaccines.