Barer G M, Pankova S N, Volozhin A I
Stomatologiia (Mosk). 1989 Sep-Oct;68(5):34-7.
A total of 104 subject were investigated and divided into 3 groups: 1. virtually healthy, without any clinical sign of periodontal inflammation; 2. periodontitis patients without internal organs affliction; 3. patients with renal pathology in which periodontitis was a concomitant disease. Biochemical investigation of the blood, oral and gingival fluids was performed. The peculiarities of periodontal involvement into renal pathology were established with lactate dehydrogenase and acid phosphatase both considerably activated in the oral and gingival fluids in groups 2 and 3. These enzymes were also activated in patients with chronic renal diseases.
共对104名受试者进行了调查,并将其分为3组:1. 基本健康,无任何牙周炎临床症状;2. 无内脏疾病的牙周炎患者;3. 患有肾脏疾病且牙周炎为伴随疾病的患者。对血液、口腔和龈沟液进行了生化检测。通过乳酸脱氢酶和酸性磷酸酶确定了牙周炎与肾脏疾病的关联特点,这两种酶在第2组和第3组的口腔和龈沟液中均显著激活。这些酶在慢性肾病患者中也被激活。