Efimenko Anastassia, Sagaradze Georgiy, Akopyan Zhanna, Lopatina Tatiana, Kalinina Natalia
Faculty of Medicine, Lomonosov Moscow State University, 31-5, Lomonosovsky av, Moscow 119191 Russia.
Data Brief. 2015 Dec 17;6:295-310. doi: 10.1016/j.dib.2015.12.021. eCollection 2016 Mar.
This article contains the full list of miRNAs expressed in cultured mesenchymal stromal cells, which were isolated from human adipose tissue. We provide here data regarding the effect of miR-92a overexpression on MSCs viability and cellular content of HGF and angiopoietin-1. These are followed by the data regarding the effect of conditioned medium of MSC transfected with pre-miR-92a, anti-miR-92a or scramble oligos on HUVEC viability as well as their tube formation efficiency. We also demonstrate here data regarding the effect of extracellular vesicle depletion from MSCs conditioned medium on its ability to stimulate the tube formation by HUVEC. Data interpretation and discussion can be found in Kalinina et al. (2015) [1].
本文包含了从人脂肪组织分离培养的间充质基质细胞中表达的miRNA完整列表。我们在此提供了关于miR-92a过表达对间充质干细胞活力以及肝细胞生长因子（HGF）和血管生成素-1细胞含量影响的数据。随后是关于用pre-miR-92a、抗miR-92a或乱序寡核苷酸转染的间充质干细胞条件培养基对人脐静脉内皮细胞（HUVEC）活力及其管形成效率影响的数据。我们还在此展示了关于从间充质干细胞条件培养基中去除细胞外囊泡对其刺激人脐静脉内皮细胞管形成能力影响的数据。数据解读和讨论可在Kalinina等人（2015年）[1]中找到。
