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麻醉后出现谵妄或疼痛——如何在幼儿中区分两者:观察性研究的回顾性分析。

Emergence delirium or pain after anaesthesia--how to distinguish between the two in young children: a retrospective analysis of observational studies.

机构信息

Department of Anaesthesia, Ca' Granda Niguarda Hospital, Milan Bicocca University, Piazza Dell'Ospedale Maggiore, Milan, Italy

Department of Anaesthesiology, Royal Aberdeen Children's Hospital, Foresterhill Rd, Aberdeen, UK.

出版信息

Br J Anaesth. 2016 Mar;116(3):377-83. doi: 10.1093/bja/aev552.

DOI:10.1093/bja/aev552
PMID:26865130
Abstract

BACKGROUND

Early postoperative negative behaviour in preschool children after general anaesthesia is a common problem. The distinction between emergence delirium (ED) and pain is difficult, but management differs between the two. The aim of the current analysis was to identify individual observational variables that can be used to diagnose ED and allow distinction from postoperative pain.

METHODS

This retrospective analysis of data from three previous prospective observational studies included children undergoing general anaesthesia for elective adeno-tonsillectomy, sub-umbilical surgery, and MRI scanning. Two trained observers simultaneously applied the Face, Legs, Activity, Cry, Consolability Scale; the Children's Hospital Eastern Ontario Pain Scale; the Children's and Infants' Postoperative Pain Scale or the Paediatric Anaesthesia Emergence Delirium (PAED) scale. Data from each domain of the scales were available at awakening and at five, 10, and 15 min after anaesthesia. Each patient was analysed over time, and subsequently, each evaluation was considered as a single event. The descriptive behaviour items overlapping in the assessed scales were identified as dichotomous variable ('true/false') and then were applied for each evaluation.

RESULTS

Children (n=512) were assessed for a total of 2048 evaluations. Most children (69%) displayed at least one episode of ED and/or pain. Almost 15% of children demonstrated both ED and pain. Children with ED showed 'no eye contact' and 'no awareness of surroundings'. Children with pain displayed 'abnormal facial expression', 'crying', and 'inconsolability'.

CONCLUSIONS

'No eye contact' and 'no awareness of surroundings' identifies ED. 'Abnormal facial expression', 'crying', and 'inconsolability' indicate acute pain in children in the early postoperative period.

摘要

背景

幼儿全身麻醉后早期的负面行为是一个常见问题。区分谵妄(ED)和疼痛很困难,但两者的处理方法不同。目前分析的目的是确定可用于诊断 ED 并将其与术后疼痛区分开来的个体观察变量。

方法

本回顾性分析来自三项先前前瞻性观察研究的数据,包括接受全身麻醉行腺样体切除术、脐下手术和 MRI 扫描的儿童。两名经过培训的观察者同时应用面部、腿部、活动、哭闹、安抚评分量表;东安大略儿童医院疼痛量表;儿童和婴儿术后疼痛量表或小儿麻醉苏醒期谵妄量表。在麻醉后苏醒时以及 5、10 和 15 分钟时,每个量表的每个域的数据都可用。对每个患者进行时间分析,然后将每个评估视为单个事件。评估中重叠的描述性行为项目被确定为二项变量(“真/假”),然后应用于每个评估。

结果

对 512 名儿童进行了总共 2048 次评估。大多数儿童(69%)至少出现一次 ED 和/或疼痛发作。近 15%的儿童同时出现 ED 和疼痛。有 ED 的儿童表现为“无眼神接触”和“无周围环境意识”。有疼痛的儿童表现为“面部表情异常”、“哭泣”和“无法安抚”。

结论

“无眼神接触”和“无周围环境意识”可识别 ED。“面部表情异常”、“哭泣”和“无法安抚”表明儿童在术后早期有急性疼痛。

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