Davies Lucy, Qi Tham Shu, Ng Agnes
Department of Pediatric Anesthesiology, KK Women and Children's Hospital, Singapore.
Anesth Pain Med (Seoul). 2024 Oct;19(Suppl 1):S87-S95. doi: 10.17085/apm.24013. Epub 2024 Jul 24.
Emergence delirium remains a clinically significant issue, which often leads to distress among pediatric patients, parents, and staff in the short term; and may also result in postoperative maladaptive behaviors persisting for weeks to months. Although several diagnostic tools are available, the Pediatric Anesthesia Emergence Delirium Scale is most often utilized. Many risk factors contributing to the likelihood of a pediatric patient developing emergence delirium have been identified; however, its accurate prediction remains challenging. Recently, intraoperative electroencephalographic monitoring has been used to improve the prediction of emergence delirium. Similarly, it may also prevent emergence delirium if the anesthesiologist ensures that the at-risk patient rouses only after the onset of appropriate electroencephalogram patterns, thus indicating a change to natural sleep. Prediction of at-risk patients is crucial; preventing emergence delirium may begin early during patient preparation by using non-pharmacological methods (i.e., the ADVANCE program). Intraoperative electroencephalographic monitoring can predict emergence delirium. This review also discusses a range of pharmacological treatment options which may assist the anesthesiologist in preventing emergence delirium among at-risk patients.
苏醒期谵妄仍然是一个具有临床重要性的问题,短期内常导致儿科患者、家长及医护人员感到困扰;还可能导致术后适应不良行为持续数周甚至数月。尽管有多种诊断工具可供使用,但小儿麻醉苏醒期谵妄量表最为常用。许多导致儿科患者发生苏醒期谵妄可能性增加的危险因素已被识别;然而,对其进行准确预测仍然具有挑战性。近来,术中脑电图监测已被用于改善对苏醒期谵妄的预测。同样,如果麻醉医生确保处于风险中的患者仅在出现适当脑电图模式后才苏醒,从而表明已转变为自然睡眠状态,那么这也可能预防苏醒期谵妄。对处于风险中的患者进行预测至关重要;通过使用非药物方法(即ADVANCE计划),在患者准备阶段早期就可开始预防苏醒期谵妄。术中脑电图监测能够预测苏醒期谵妄。本综述还讨论了一系列药物治疗选择,这些选择可能有助于麻醉医生预防处于风险中的患者发生苏醒期谵妄。