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先天性肾上腺皮质增生症患者成功妊娠并分娩。

Successful pregnancy and delivery of a patient with congenital adrenal hyperplasia.

作者信息

Mun Da Hyun, Yun Ha Na, Kim Jong Woon, Kim Yoon Ha, Song Tae-Bok

机构信息

Department of Obstetrics and Gynecology, Chonnam National University Medical School, Gwangju, Korea.

出版信息

Obstet Gynecol Sci. 2016 Jan;59(1):50-3. doi: 10.5468/ogs.2016.59.1.50. Epub 2016 Jan 15.

Abstract

Congenital adrenal hyperplasia (CAH) during pregnancy is a rare condition. Only a few cases have been reported in the literature. CAH patients has lower pregnancy rate compared to normal women. A 27-year-old nulliparous woman, a diagnosed case of 21-hydroxylase deficient simple virilising form of classic CAH visited. She got pregnant spontaneously without any trial of assisted reproductive technology. At the age of 12, she underwent clitoral resection and vaginoplasty. She took dexamethasone or prednisolone after operation. She delivered healthy singleton female baby by cesarean section. Four years later, she delivered healthy singleton female baby by repeat cesarean section. Two female babies have shown normal external genitalia. Here, we report a case of successful pregnancy and delivery in a patient with CAH.

摘要

孕期先天性肾上腺皮质增生症(CAH)是一种罕见疾病。文献中仅报道过少数病例。与正常女性相比,CAH患者的妊娠率较低。一名27岁未生育女性前来就诊,她被诊断为经典型CAH中21-羟化酶缺乏单纯男性化型。她未经任何辅助生殖技术尝试便自然受孕。12岁时,她接受了阴蒂切除术和阴道成形术。术后她服用地塞米松或泼尼松龙。她通过剖宫产分娩出一名健康的单胎女婴。四年后,她再次通过剖宫产分娩出一名健康的单胎女婴。两名女婴的外生殖器均显示正常。在此,我们报告一例CAH患者成功妊娠及分娩的病例。

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