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急性肺栓塞的30天死亡率:临床评分和既往史特征的预后价值

30-Day Mortality in Acute Pulmonary Embolism: Prognostic Value of Clinical Scores and Anamnestic Features.

作者信息

Bach Andreas Gunter, Taute Bettina-Maria, Baasai Nansalmaa, Wienke Andreas, Meyer Hans Jonas, Schramm Dominik, Surov Alexey

机构信息

Department of Radiology, Martin-Luther-University Halle-Wittenberg, Ernst-Grube-Str. 40, 06120 Halle, Germany.

Department of Internal Medicine, Martin-Luther-University Halle-Wittenberg, Ernst-Grube-Str. 40, 06120 Halle, Germany.

出版信息

PLoS One. 2016 Feb 11;11(2):e0148728. doi: 10.1371/journal.pone.0148728. eCollection 2016.

Abstract

PURPOSE

Identification of high-risk patients with pulmonary embolism is vital. The aim of the present study was to examine clinical scores, their single items, and anamnestic features in their ability to predict 30-day mortality.

MATERIALS AND METHODS

A retrospective, single-center study from 06/2005 to 01/2010 was performed. Inclusion criteria were presence of pulmonary embolism, availability of patient records and 30-day follow-up. The following clinical scores were calculated: Acute Physiology and Chronic Health Evaluation II, original and simplified pulmonary embolism severity index, Glasgow Coma Scale, and euroSCORE II.

RESULTS

In the study group of 365 patients 39 patients (10.7%) died within 30 days due to pulmonary embolism. From all examined scores and parameters the best predictor of 30-day mortality were the Glasgow Coma scale (≤ 10) and parameters of the circulatory system including presence of mechanical ventilation, arterial pH (< 7.335), and systolic blood pressure (< 99 mm Hg).

CONCLUSIONS

Easy to ascertain circulatory parameters have the same or higher prognostic value than the clinical scores that were applied in this study. From all clinical scores studied the Glasgow Coma Scale was the most time- and cost-efficient one.

摘要

目的

识别肺栓塞高危患者至关重要。本研究旨在检验临床评分、其单项指标以及既往特征预测30天死亡率的能力。

材料与方法

进行了一项从2005年6月至2010年1月的回顾性单中心研究。纳入标准为存在肺栓塞、有患者记录且随访30天。计算了以下临床评分:急性生理与慢性健康状况评分II、原始及简化肺栓塞严重程度指数、格拉斯哥昏迷量表和欧洲心脏手术风险评估系统II。

结果

在365例患者的研究组中,39例患者(10.7%)在30天内因肺栓塞死亡。在所有检查的评分和参数中,30天死亡率的最佳预测指标是格拉斯哥昏迷量表(≤10)以及循环系统参数,包括机械通气的存在、动脉pH值(<7.335)和收缩压(<99mmHg)。

结论

易于确定的循环参数与本研究中应用的临床评分具有相同或更高的预后价值。在所有研究的临床评分中,格拉斯哥昏迷量表是最节省时间和成本的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48d2/4750907/8ba61b42f338/pone.0148728.g001.jpg

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