Rossbach O, Bindereif A
Pharmazie. 2016 Jan;71(1):3-7.
Non-coding RNAs (ncRNAs) in eukaryotes have recently developed to a very active research area in RNA biology, opening up new strategies for diagnosis and therapies of human disease. Here we introduce and describe the most important classes of eukaryotic ncRNAs: microRNAs (miRNAs), long non-coding RNAs (IncRNAs), and circular RNAs (circRNAs). We further discuss new RNA-based diagnostic and therapeutic concepts.
真核生物中的非编码RNA（ncRNAs）最近已发展成为RNA生物学中一个非常活跃的研究领域，为人类疾病的诊断和治疗开辟了新策略。在这里，我们介绍并描述真核生物ncRNAs的最重要类别：微小RNA（miRNAs）、长链非编码RNA（lncRNAs）和环状RNA（circRNAs）。我们还将进一步讨论基于RNA的新诊断和治疗概念。
