Schmitt G, Littmann K
Strahlentherapie. 1977 Aug;153(8):538-42.
The authors describe six observations of malignant tumors which had appeared in the region of the irradiation fields after a period of 11 to 51 years following to a radiotherapy. The doses were between approximately 2000 and 9000 R resp. rd. The individual tumors were: one osteogenic sarcoma, one chondrosarcoma, two fibrosarcomas, one lymphangio-hemangio-sarcoma and one basal cell carcinoma. According to the present state of our knowledge about the induction of tumors by ionizing radiation, we presume that no threshold dose does exist and that the danger of a tumor induction increases with the dose. The function of the tumor induction is still in general discussion.
作者描述了6例恶性肿瘤观察病例，这些肿瘤是在放疗后11至51年期间出现在照射野区域的。剂量分别约为2000至9000伦琴（拉德）。具体肿瘤类型为：1例骨肉瘤、1例软骨肉瘤、2例纤维肉瘤、1例淋巴管 - 血管肉瘤和1例基底细胞癌。根据我们目前对电离辐射诱发肿瘤的认识，我们推测不存在阈剂量，且诱发肿瘤的风险随剂量增加而升高。肿瘤诱发的机制仍在广泛讨论中。
