早期胃癌淋巴结转移的预测因素：一项临床研究。
The predictive factors for lymph node metastasis in early gastric cancer: A clinical study.
作者信息
Wang Yinzhong
机构信息
Yinzhong Wang, MD. Department of General surgery, The Second People's Hospital of Jiaozuo, Jiaozuo, Henan province, China.
出版信息
Pak J Med Sci. 2015 Nov-Dec;31(6):1437-40. doi: 10.12669/pjms.316.8247.
OBJECTIVE
To detect the clinicopathological factors associated with lymph node metastases in early gastric cancer.
METHODS
We retrospectively evaluated the distribution of metastatic nodes in 198 patients with early gastric cancer treated in our hospital between May 2008 and January 2015, the clinicopathological factors including age, gender, tumor location, tumor size, macroscopic type, depth of invasion, histological type and venous invasion were studied, and the relationship between various parameters and lymph node metastases was analyzed.
RESULTS
In this study, one hundred and ninety-eight patients with early gastric cancer were included, and lymph node metastasis was detected in 28 patients. Univariate analysis revealed a close relationship between tumor size, depth of invasion, histological type, venous invasion, local ulceration and lymph node metastases. Multivariate analysis revealed that the five factors were independent risk factors for lymph node metastases.
CONCLUSION
The clinicopathological parameters including tumor size, depth of invasion, local ulceration, histological type and venous invasion are closely correlated with lymph node metastases, should be paid high attention in early gastric cancer patients.
目的
检测早期胃癌中与淋巴结转移相关的临床病理因素。
方法
回顾性评估2008年5月至2015年1月在我院接受治疗的198例早期胃癌患者转移淋巴结的分布情况，研究包括年龄、性别、肿瘤位置、肿瘤大小、大体类型、浸润深度、组织学类型和静脉侵犯在内的临床病理因素，并分析各项参数与淋巴结转移之间的关系。
结果
本研究纳入198例早期胃癌患者，其中28例检测到淋巴结转移。单因素分析显示肿瘤大小、浸润深度、组织学类型、静脉侵犯、局部溃疡与淋巴结转移密切相关。多因素分析显示这五个因素是淋巴结转移的独立危险因素。
结论
肿瘤大小、浸润深度、局部溃疡、组织学类型和静脉侵犯等临床病理参数与淋巴结转移密切相关，在早期胃癌患者中应予以高度重视。
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