[早期胃癌淋巴结转移危险因素的多因素分析]
[Multivariate analysis of risk factors of lymph node metastasis in early gastric cancer].
作者信息
Fang Yi, Zhao Dong-bing, Zhou Jian-guo, Cai Jian-qiang
机构信息
Department of Abdominal Surgery, Cancer Hospital, Chinese Academy of Medical Sciences, Beijing 100021, China.
出版信息
Zhonghua Wei Chang Wai Ke Za Zhi. 2009 Mar;12(2):130-2.
OBJECTIVE
To investigate the clinicopathological factors affecting lymph node metastasis in early gastric cancer(EGC).
METHODS
Clinicopathological data of 369 patients with EGC from Jan. 1999 to Jun. 2008 were analyzed retrospectively. Multivariate analysis was performed to find the risk factors affecting lymph node metastasis.
RESULTS
The age, gender, tumor size, invasion depth, histological classification and vascular cancer thrombosis were associated with lymph node metastasis. Multivariate analysis showed that tumor size and depth of invasion were main independent risk factors.
CONCLUSIONS
The main independent risk factors affecting lymph node metastasis in EGC are tumor size and invasion depth. The gender, vascular cancer thrombosis, tumor size, invasion depth and histological classification should be considered to establish the surgical program.
目的
探讨影响早期胃癌（EGC）淋巴结转移的临床病理因素。
方法
回顾性分析1999年1月至2008年6月期间369例EGC患者的临床病理资料。进行多因素分析以找出影响淋巴结转移的危险因素。
结果
年龄、性别、肿瘤大小、浸润深度、组织学分类和癌栓与淋巴结转移有关。多因素分析显示肿瘤大小和浸润深度是主要的独立危险因素。
结论
影响EGC淋巴结转移的主要独立危险因素是肿瘤大小和浸润深度。制定手术方案时应考虑性别、癌栓、肿瘤大小、浸润深度和组织学分类。
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