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非特异性背痛的当前问题

THE CURRENT PROBLEMS OF NONSPECIFIC BACK PAIN.

作者信息

Seleznova S, Zabara A, Mamuladze D

机构信息

Donetsk State Medical University named after M. Gorky, Department of Neurology, Neurosurgery and Medical Genetics; Medical Center Ukrgeorgmedical, Batumi; Batumi Referral Hospital, Georgia.

出版信息

Georgian Med News. 2016 Jan(250):61-6.

Abstract

The article deals with various aspects of pain in degenerative diseases of the spine and with the actual problems of non-specific back pain. The data on the mechanisms of pain and analgesic treatment algorithms of the patients with radicular syndrome, and pharmacological and non-pharmacological therapies is provided. The effect of structural-modifying drugs in relief of nonspecific back pain was investigated and compared with a traditional nonsteroidal anti-inflammatory drug (NSAID) therapy in combination with B vitamins, without chondroprotectors. The study population was composed of 85 patients (42 men and 43 women) aged 38 to 68 years (mean age - (46,3±2,6) years) with chronic vertebral pain syndromes (VPS). For objectification assessment of pain, severity of pain, and evaluate the effectiveness of therapy we used the visual analog scale (VAS).The majority (88%) of the patients included in the study, complained of a moderately severe pain (from 40 to 70 mm on the VAS). Patients were divided into two groups. The first (primary) group consisted of 55 patients (30 men and 25 women). The following treatment was applied: all patients of the first group, in addition to the NSAID administered with hondroprotektror arbitrarily - Struktum 1000 mg twice a day or 300 mg Piaskledin once a day for 40-60 days.The second (control) group consisted of 30 patients (14 men, 16 women). Patients in the control group administered with a traditional NSAID therapy in combination with B vitamins, without chondroprotectors. The results of the study on the influence of drugs Piaskledin 300, Struktum for the relief of nonspecific back pain revealed that in the treatment of vertebral pain, a combination of non-steroidal anti-inflammatory drugs with structure-modifying agents could achieve rapid rehabilitation of patients with locomotor activity and improve quality of life in general.

摘要

本文探讨了脊柱退行性疾病疼痛的各个方面以及非特异性背痛的实际问题。提供了有关根性综合征患者疼痛机制和镇痛治疗算法,以及药物和非药物疗法的数据。研究了结构改善药物缓解非特异性背痛的效果,并将其与传统非甾体抗炎药(NSAID)联合B族维生素、不使用软骨保护剂的疗法进行了比较。研究人群包括85例年龄在38至68岁(平均年龄 - (46.3±2.6)岁)的慢性脊椎疼痛综合征(VPS)患者(42名男性和43名女性)。为了客观评估疼痛、疼痛严重程度并评估治疗效果,我们使用了视觉模拟量表(VAS)。纳入研究的大多数患者(88%)主诉中度至重度疼痛(VAS评分40至70毫米)。患者分为两组。第一(主要)组由55名患者(30名男性和25名女性)组成。采用以下治疗方法:第一组的所有患者,除了随意给予的NSAID与软骨保护剂外 - Struktum每天两次,每次1000毫克,或Piaskledin每天一次,每次300毫克,持续40 - 60天。第二(对照)组由30名患者(14名男性,16名女性)组成。对照组患者采用传统NSAID联合B族维生素治疗,不使用软骨保护剂。关于Piaskledin 300、Struktum药物对缓解非特异性背痛影响的研究结果表明,在治疗脊椎疼痛时,非甾体抗炎药与结构改善剂联合使用可以使患者的运动活动迅速恢复,并总体提高生活质量。

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