Cooper J W
Department of Pharmacy Practice, College of Pharmacy, University of Georgia, Athens.
Geriatrics. 1989 Dec;44(12):79-86.
The most important special consideration for drug use in the last years of life is that the medications prescribed do what is intended and do not contribute to morbidity or premature mortality. Key factors in appropriate use are reviewed for analgesics, anti-inflammatories, corticosteroids, thyroid drugs, anti-diabetic agents, digoxin, newer antiarrhythmics, beta-blockers, diuretics and potassium supplements, sympatholytic and vasodilatory antihypertensives, warfarin and heparin, anxiolytics, neuroleptics, anticonvulsants, antidepressants, antimicrobials, laxatives, gastrointestinal and bronchodilatory agents, and nutritional supplements and vitamins.
生命最后几年用药最重要的特殊考量是，所开药物要达到预期效果，且不会导致发病或过早死亡。本文回顾了合理用药的关键因素，涉及镇痛药、抗炎药、皮质类固醇、甲状腺药物、抗糖尿病药物、地高辛、新型抗心律失常药、β受体阻滞剂、利尿剂和钾补充剂、抗交感神经和血管舒张性抗高血压药、华法林和肝素、抗焦虑药、抗精神病药、抗惊厥药、抗抑郁药、抗菌药、泻药、胃肠道和支气管扩张剂，以及营养补充剂和维生素。
