Wang Yuan-da, Dong Zhe-yi, Zhang Xue-guang, Zhang Wei, Yin Zhong, Qiu Qiang, Chen Xiang-mei
Department of Nephrology, Chinese PLA General Hospital, Chinese PLA Institute of Nephrology, State Key Laboratory of Kidney Diseases, National Clinical Research Center of Kidney Diseases, China.
Intern Med. 2016;55(4):369-73. doi: 10.2169/internalmedicine.55.4443. Epub 2016 Feb 15.
We herein report the case of an elderly woman with bone pain and proteinuria as the main clinical manifestations. The patient was diagnosed with the IgG κ type of multiple myeloma. Her renal pathology consisted of widespread κ light chain protein deposition associated with the formation of large quantities of rod-like crystals in podocytes. This phenomenon is very rare. We explored the significance of this crystal formation via a detailed and descriptive analysis and also performed a literature review, thus providing data to increase the available information about this type of disease.
我们在此报告一例以骨痛和蛋白尿为主要临床表现的老年女性病例。该患者被诊断为IgG κ型多发性骨髓瘤。她的肾脏病理表现为广泛的κ轻链蛋白沉积,并伴有足细胞内大量棒状晶体形成。这种现象非常罕见。我们通过详细的描述性分析探讨了这种晶体形成的意义,并进行了文献综述,从而提供数据以增加关于此类疾病的可用信息。