Xiao W-L, Zhang D-Z, Chen X-J, Yuan C, Xue L-F
Department of Stomatology, The Affiliated Hospital of Qingdao University, Qingdao, China; The Key Laboratory of Oral Clinical Medicine of Shandong Province, The Affiliated Hospital of Qingdao University, Qingdao, China.
Department of Stomatology, The Affiliated Hospital of Qingdao University, Qingdao, China; The Key Laboratory of Oral Clinical Medicine of Shandong Province, The Affiliated Hospital of Qingdao University, Qingdao, China.
Int J Oral Maxillofac Surg. 2016 Jun;45(6):683-7. doi: 10.1016/j.ijom.2016.01.013. Epub 2016 Feb 11.
Cone beam computed tomography (CBCT) allows for a significantly lower radiation dose than conventional computed tomography (CT) scans and provides accurate images of the alveolar cleft area. The osteogenic effect of guided bone regeneration (GBR) vs. conventional alveolar bone grafting alone for alveolar cleft defects was evaluated in this study. Sixty alveolar cleft patients were divided randomly into two groups. One group underwent GBR using acellular dermal matrix film combined with alveolar bone grafting using iliac crest bone grafts (GBR group), while the other group underwent alveolar bone grafting only (non-GBR group). CBCT images were obtained at 1 week and at 3 months following the procedure. Using Simplant 11.04 software, the bone resorption rate was calculated and compared between the two groups. The bone resorption rate from 1 week to 3 months following bone grafting without the GBR technique was 36.50±5.04%, whereas the bone resorption rate using the GBR technique was 31.69±5.50% (P=0.017). The application of autogenous iliac bone combined with the GBR technique for alveolar bone grafting of alveolar cleft patients can reduce bone resorption and result in better osteogenesis.
锥形束计算机断层扫描（CBCT）的辐射剂量明显低于传统计算机断层扫描（CT），并能提供牙槽裂区域的精确图像。本研究评估了引导骨再生（GBR）与单纯传统牙槽骨移植对牙槽裂缺损的成骨效果。60例牙槽裂患者被随机分为两组。一组采用脱细胞真皮基质膜联合髂嵴骨移植进行GBR（GBR组），另一组仅进行牙槽骨移植（非GBR组）。术后1周和3个月获取CBCT图像。使用Simplant 11.04软件计算并比较两组的骨吸收速率。未采用GBR技术的骨移植术后1周到3个月的骨吸收速率为36.50±5.04%，而采用GBR技术的骨吸收速率为31.69±5.50%（P=0.017）。自体髂骨联合GBR技术应用于牙槽裂患者的牙槽骨移植可减少骨吸收并产生更好的成骨效果。
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