Johnson Sheri L, Cuellar Amy K, Gershon Anda
Department of Psychology, University of California Berkeley, 3210 Tolman Hall, MC 1650, Berkeley, CA 94720-1659, USA.
Michael E. DeBakey VA Medical Center, Houston, TX, USA; Baylor College of Medicine, Menninger Department of Psychiatry and Behavioral Sciences, 1 Baylor Plaza, Houston, TX 77030, USA.
Psychiatr Clin North Am. 2016 Mar;39(1):87-94. doi: 10.1016/j.psc.2015.09.003. Epub 2015 Dec 22.
A growing body of research suggests that the social environment exerts a powerful influence on the course of bipolar depression. This article reviews longitudinal research to suggest that trauma, negative life events, social support deficits, and family difficulties are common and predict a more severe course of depression when present among those diagnosed with bipolar disorder. The triggers of bipolar depression overlap with those documented for unipolar depression, suggesting that many of the treatment targets for unipolar depression may be applicable for bipolar depression.
越来越多的研究表明，社会环境对双相抑郁症的病程有着强大的影响。本文回顾了纵向研究，结果表明创伤、负面生活事件、社会支持不足和家庭困难很常见，并且在被诊断为双相情感障碍的患者中出现时，预示着抑郁病程会更严重。双相抑郁症的触发因素与单相抑郁症所记录的触发因素重叠，这表明单相抑郁症的许多治疗靶点可能适用于双相抑郁症。
