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High levels of the c-myc protein in cell lines of Bloom's syndrome origin.

作者信息

Sullivan N F, Willis A E, Moore J P, Lindahl T

机构信息

Imperial Cancer Research Fund, Clare Hall Laboratories, South Mimms, Hert, U.K.

出版信息

Oncogene. 1989 Dec;4(12):1509-11.

PMID:2687770
Abstract

Lymphoblastoid cell lines derived from cancer prone Bloom's Syndrome patients differ from cell lines representative of several other disorders by exhibiting a constitutive elevation in the level of the c-myc protein. This may be a contributing factor in the strong predisposition to malignancy observed in Bloom's syndrome.

摘要

相似文献

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