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骨髓增生异常综合征伴难治性血细胞减少伴多系发育异常患者的膜性肾小球肾炎。

Membranous glomerulonephritis in a patient with myelodysplastic syndrome-refractory cytopenia with multilineage dysplasia.

机构信息

Department of Internal Medicine, College of Medicine, Yonsei University, Seoul, Korea.

出版信息

Kidney Res Clin Pract. 2013 Sep;32(3):134-7. doi: 10.1016/j.krcp.2013.06.001. Epub 2013 Jul 10.

Abstract

A 74-year-old woman presented with edema in the lower extremities. Laboratory tests revealed anemia, thrombocytopenia, hypoalbuminemia, hypercholesterolemia, and nephrotic-range proteinuria. Myelodysplastic syndrome-refractory cytopenia with multilineage dysplasia (MDS-RCMD) was confirmed by bone marrow biopsy. Renal biopsy demonstrated membranous glomerulonephritis (MGN), stage I. Based on these clinicopathologic results, she was diagnosed as having MGN with MDS-RCMD. This is a rare case report of MGN in a parient with MDS-RCMD featuring nephrotic syndrome.

摘要

一位 74 岁女性出现下肢水肿。实验室检查显示贫血、血小板减少、低白蛋白血症、高胆固醇血症和肾病范围蛋白尿。骨髓活检证实为骨髓增生异常综合征难治性血细胞减少伴多系发育异常(MDS-RCMD)。肾脏活检显示膜性肾小球肾炎(MGN),I 期。根据这些临床病理结果,诊断为 MDS-RCMD 合并 MGN。这是一例罕见的 MDS-RCMD 患者发生肾病综合征合并 MGN 的病例报告。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7b5/4714092/a94a6a92560f/gr1.jpg

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