电脑鼠标移动模式：轻度认知障碍的潜在标志物。
Computer mouse movement patterns: A potential marker of mild cognitive impairment.
作者信息
Seelye Adriana, Hagler Stuart, Mattek Nora, Howieson Diane B, Wild Katherine, Dodge Hiroko H, Kaye Jeffrey A
机构信息
Oregon Health & Science University, Department of Neurology, Portland, Oregon; Oregon Health & Science University, Oregon Center for Aging and Technology, Portland, Oregon.
Northeastern University, Boston, Massachusetts.
出版信息
Alzheimers Dement (Amst). 2015 Dec 1;1(4):472-480. doi: 10.1016/j.dadm.2015.09.006. Epub 2015 Oct 19.
INTRODUCTION
Subtle changes in cognitively demanding activities occur in MCI but are difficult to assess with conventional methods. In an exploratory study, we examined whether patterns of computer mouse movements obtained from routine home computer use discriminated between older adults with and without MCI.
METHODS
Participants were 42 cognitively intact and 20 older adults with MCI enrolled in a longitudinal study of in-home monitoring technologies. Mouse pointer movement variables were computed during one week of routine home computer use using algorithms that identified and characterized mouse movements within each computer use session.
RESULTS
MCI was associated with making significantly fewer total mouse moves (<.01), and making mouse movements that were more variable, less efficient, and with longer pauses between movements (<.05). Mouse movement measures were significantly associated with several cognitive domains ('s<.01-.05).
DISCUSSION
Remotely monitored computer mouse movement patterns are a potential early marker of real-world cognitive changes in MCI.
引言
轻度认知障碍（MCI）患者在需要认知能力的活动中会出现细微变化，但用传统方法难以评估。在一项探索性研究中，我们研究了从日常家庭电脑使用中获取的电脑鼠标移动模式能否区分患有和未患有MCI的老年人。
方法
参与者包括42名认知功能正常的老年人和20名患有MCI的老年人，他们参与了一项关于家庭监测技术的纵向研究。在一周的日常家庭电脑使用期间，使用算法计算鼠标指针移动变量，该算法可识别并描述每次电脑使用会话中的鼠标移动。
结果
MCI与总鼠标移动次数显著减少（<.01）相关，且鼠标移动更具变异性、效率更低，移动之间的停顿时间更长（<.05）。鼠标移动测量与几个认知领域显著相关（<.01-.05）。
讨论
远程监测的电脑鼠标移动模式是MCI患者现实世界认知变化的潜在早期标志物。
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