Liu Bin, Wang Xin, Ge Zemei, Li Runtao
Skate Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China.
Org Biomol Chem. 2016 Mar 14;14(10):2944-9. doi: 10.1039/c6ob00179c.
Herein we report a novel iridium(iii)-catalyzed ortho-mono-alkynylation of 7-azaindoles under mild conditions. This approach provides a general and straightforward access to form novel 7-azaindole derivatives with ample substrate scope and broad group tolerance.
在此，我们报道了一种在温和条件下铱(III)催化的7-氮杂吲哚邻位单炔基化反应。该方法提供了一种通用且直接的途径，可用于合成具有广泛底物范围和基团耐受性的新型7-氮杂吲哚衍生物。
