School of Medicine, The University of Queensland, Brisbane, Australia.
Department of Otolaryngology-Head and Neck Surgery, The Queen Elizabeth Hospital, Woodville, Australia.
Int Forum Allergy Rhinol. 2016 May;6(5):518-22. doi: 10.1002/alr.21715. Epub 2016 Feb 16.
Endoscopic modified Lothrop procedure (EMLP) is used to treat patients who fail conventional sinus surgery. The failure rate of a primary EMLP is reported to be between 5% and 32%. The failure rate of revision EMLP has not been reported. We present our institutions data regarding the outcome of patients requiring revision EMLP.
Data was collected prospectively. Patients undergoing primary EMLP between January 2001 and December 2013 with a minimum follow-up of 6 months were included. Information related to demographics, asthma status, aspirin sensitivity, 22-item Sino-Nasal Outcome Test (SNOT-22) score, Lund-Mackay scores, intraoperative findings, and endoscopic ostium assessment were collected.
There were 213 primary EMLPs completed with average follow-up of 36 months. The failure rate of primary EMLP was 8.9% (19/213), whereas the failure rate of revision EMLP was 21% (4/19). Risk factors for failure of primary EMLP included the presence of intraoperative pus, more than 5 previous sinus operations and aspirin-exacerbated respiratory disease (AERD). Revision of EMLP was undertaken primarily due to recurrence of nasal polyps or ostium stenosis. Those patients who underwent revision EMLP experienced symptomatic improvement and no major complications following the procedure.
The failure rate of revision EMLP is 21% in our series. The majority of revisions were for nasal polyp recurrence. Revision EMLP is a safe and well-tolerated procedure in the small group of patients that require further surgery. Patients with intraoperative pus present at their initial EMLP, more than 5 previous sinus operations, or AERD are at increased risk of failure.
内镜改良 Lothrop 手术(EMLP)用于治疗常规鼻窦手术失败的患者。初次 EMLP 的失败率报道在 5%至 32%之间。尚未报道翻修 EMLP 的失败率。我们报告了我们机构中需要翻修 EMLP 的患者的结果数据。
数据是前瞻性收集的。纳入 2001 年 1 月至 2013 年 12 月期间接受初次 EMLP 的患者,且随访时间至少为 6 个月。收集了与人口统计学、哮喘状况、阿司匹林敏感性、22 项鼻-鼻窦结局测试(SNOT-22)评分、Lund-Mackay 评分、术中发现和内镜口评估相关的信息。
完成了 213 例初次 EMLP,平均随访 36 个月。初次 EMLP 的失败率为 8.9%(19/213),而翻修 EMLP 的失败率为 21%(4/19)。初次 EMLP 失败的风险因素包括术中有脓液、超过 5 次鼻窦手术和阿司匹林加重的呼吸道疾病(AERD)。翻修 EMLP 主要是由于鼻息肉复发或口狭窄。接受翻修 EMLP 的患者在手术后症状改善,无重大并发症。
在我们的系列中,翻修 EMLP 的失败率为 21%。大多数翻修是为了鼻息肉复发。在需要进一步手术的少数患者中,翻修 EMLP 是一种安全且耐受良好的手术。在初次 EMLP 术中存在脓液、超过 5 次鼻窦手术或 AERD 的患者失败风险增加。