Sharopov Farukh S, Satyal Prabodh, Ali Nasser A Awadh, Pokharel Suraj, Zhang Hanjing, Wink Michael, Kukaniev Muhammadsho A, Setzer William N
Institute of Pharmacy and Molecular Biotechnology, Heidelberg University, Im Neuenheimer Feld 364, DE-69120 Heidelberg.
Department of Chemistry, University of Alabama in Huntsville, Huntsville, AL 35899, USA, (phone: +1-256-824-6519; fax: +1-256-824-6519).
Chem Biodivers. 2016 Feb;13(2):241-8. doi: 10.1002/cbdv.201500108.
The aerial parts of Ocimum basilicum L. were collected from four different geographical locations, Sindhuli and Biratnagar (Nepal), Chormaghzak village (Tajikistan), and Sana'a (Yemen). The essential oils were obtained by hydrodistillation and analyzed by gas chromatography/mass spectrometry. A cluster analysis of 179 essential oil compositions revealed six major chemotypes: Linalool, eugenol, estragole, methyl eugenol, 1,8-cineole, and geraniol. All four of the basil oils in this study were of the linalool-rich variety. Some of the basil oils were screened for bioactivity including antimicrobial, cytotoxicity in human cancer cells, brine shrimp lethality, nematicidal, larvicidal, insecticidal, and antioxidant. The basil oils in this study were not notably antibacterial, cytotoxic, antioxidant, nor nematicidal, but were active in the brine shrimp lethality test, and did show larvicidal and insecticidal activities.
罗勒（Ocimum basilicum L.）的地上部分采自四个不同地理位置，即尼泊尔的辛杜利和比拉特纳格尔、塔吉克斯坦的乔尔马格扎克村以及也门的萨那。通过水蒸馏法获得挥发油，并采用气相色谱/质谱联用仪进行分析。对179种挥发油成分进行聚类分析，结果显示有六种主要化学型：芳樟醇、丁香酚、草蒿脑、甲基丁香酚、1,8-桉叶素和香叶醇。本研究中的四种罗勒油均富含芳樟醇。对部分罗勒油进行了生物活性筛选，包括抗菌活性、对人癌细胞的细胞毒性、卤虫致死性、杀线虫活性、杀幼虫活性、杀虫活性和抗氧化活性。本研究中的罗勒油在抗菌、细胞毒性、抗氧化和杀线虫方面并无显著活性，但在卤虫致死性试验中表现出活性，且确实具有杀幼虫和杀虫活性。
