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Thrombin interactions with hirudin.

作者信息

Fenton J W

机构信息

Wadsworth Center for Laboratories and Research, New York State Department of Health, Albany 12201.

出版信息

Semin Thromb Hemost. 1989 Jul;15(3):265-8. doi: 10.1055/s-2007-1002718.

DOI:10.1055/s-2007-1002718
PMID:2688098
Abstract
摘要

相似文献

1
Thrombin interactions with hirudin.
Semin Thromb Hemost. 1989 Jul;15(3):265-8. doi: 10.1055/s-2007-1002718.
2
Probing the distance between the two binding sites of hirudin for its interaction with the active site and the fibrin(ogen)-binding site of alpha-thrombin.探究水蛭素两个结合位点之间的距离，以了解其与α-凝血酶活性位点及纤维蛋白（原）结合位点的相互作用。
Biomed Biochim Acta. 1991;50(4-6):707-10.
3
Structure-activity relationships of recombinant hirudins.重组水蛭素的构效关系
Semin Thromb Hemost. 1991 Apr;17(2):94-8. doi: 10.1055/s-2007-1002595.
4
Recombinant hirudin: genetic engineering and structure analysis.重组水蛭素：基因工程与结构分析
Semin Thromb Hemost. 1991 Apr;17(2):88-93. doi: 10.1055/s-2007-1002594.
5
Effects of site specific amino acid exchanges in hirudin on the thrombin-hirudin interaction.
Folia Haematol Int Mag Klin Morphol Blutforsch. 1988;115(1-2):24-9.
6
[Recent developments in the biochemistry of hirudins].
Folia Haematol Int Mag Klin Morphol Blutforsch. 1989;116(6):821-30.
7
Biochemistry and genetic engineering of hirudin.
Semin Thromb Hemost. 1989 Jul;15(3):302-15. doi: 10.1055/s-2007-1002723.
8
Isolation and characterization of hirudin from Hirudo medicinalis.
Semin Thromb Hemost. 1991 Apr;17(2):83-7. doi: 10.1055/s-2007-1002593.
9
The structure of a complex of recombinant hirudin and human alpha-thrombin.重组水蛭素与人α-凝血酶复合物的结构
Science. 1990 Jul 20;249(4966):277-80. doi: 10.1126/science.2374926.
10
Structure of the hirugen and hirulog 1 complexes of alpha-thrombin.α-凝血酶的水蛭素和水蛭素-1复合物的结构
J Mol Biol. 1991 Oct 20;221(4):1379-93.

引用本文的文献

1
Thrombin: An Approach to Developing a Higher-Order Reference Material and Reference Measurement Procedure for Substance Identity, Amount, and Biological Activities.凝血酶：开发用于物质鉴定、含量和生物活性的高阶参考物质及参考测量程序的方法。
J Res Natl Inst Stand Technol. 2020 Jul 29;125:125021. doi: 10.6028/jres.125.021. eCollection 2020.
2
The stabilization and release of hirudin from liposomes or lipid-assemblies coated with hydrophobically modified dextran.水蛭素从包覆有疏水改性葡聚糖的脂质体或脂质组装体中的稳定化及释放。
AAPS PharmSciTech. 2000 Mar 3;1(1):E3. doi: 10.1208/pt010103.
3
Thrombin stimulates proliferation of cultured rat aortic smooth muscle cells by a proteolytically activated receptor.
凝血酶通过蛋白水解激活受体刺激培养的大鼠主动脉平滑肌细胞增殖。
J Clin Invest. 1993 Jan;91(1):94-8. doi: 10.1172/JCI116206.
4
Crystal structure of the thrombin-hirudin complex: a novel mode of serine protease inhibition.凝血酶-水蛭素复合物的晶体结构：丝氨酸蛋白酶抑制的新模式。
EMBO J. 1990 Aug;9(8):2361-5. doi: 10.1002/j.1460-2075.1990.tb07410.x.
5
Generation of forms of fragment E with differing thrombin-binding properties during digestion of fibrinogen by plasmin.纤溶酶消化纤维蛋白原过程中具有不同凝血酶结合特性的片段E形式的产生。
Biochem J. 1992 Feb 1;281 ( Pt 3)(Pt 3):613-8. doi: 10.1042/bj2810613.
6
Structural differences in active site-labeled thrombin complexes with hirudin isoinhibitors.活性位点标记的凝血酶与水蛭素异抑制剂复合物的结构差异。
J Protein Chem. 1992 Oct;11(5):483-8. doi: 10.1007/BF01025025.
7
Thrombin receptor activation causes rapid neural cell rounding and neurite retraction independent of classic second messengers.凝血酶受体激活导致快速的神经细胞变圆和神经突回缩，且不依赖于经典的第二信使。
J Cell Biol. 1992 Jul;118(2):411-9. doi: 10.1083/jcb.118.2.411.
8
Catalytically competent human and bovine zeta-thrombin and chimeras generated from unfolded polypeptide chains.具有催化活性的人源和牛源ζ-凝血酶以及由未折叠多肽链产生的嵌合体。
Protein Sci. 1992 Aug;1(8):998-1006. doi: 10.1002/pro.5560010805.
9
Thrombin-specific inhibition by and slow cleavage of hirulog-1.水蛭素-1对凝血酶的特异性抑制作用及其缓慢裂解
Biochem J. 1992 May 1;283 ( Pt 3)(Pt 3):737-43. doi: 10.1042/bj2830737.