Kristensen K
Ugeskr Laeger. 1989 Nov 27;151(48):3216-8.
Haemophilus influenzae type b (Hib) causes severe invasive infections in children such as meningitis and epiglottitis. Vaccines against Hib are now available. This article describes the background for the development of these vaccines and their composition, it presents available data on immunogenicity and protective efficacy and briefly discusses the need for their use in Denmark.
b型流感嗜血杆菌(Hib)可导致儿童发生严重的侵袭性感染,如脑膜炎和会厌炎。目前已有针对Hib的疫苗。本文描述了这些疫苗的研发背景及其成分,介绍了关于免疫原性和保护效力的现有数据,并简要讨论了在丹麦使用这些疫苗的必要性。