From the Division of Nuclear Medicine (O.A.R., R.M., M.M.O.), Department of Radiology (O.A.R., N.D.P., R.M., C.D., M.M.O.), Saint Louis University, 3635 Vista Blvd at Grand Blvd, St Louis, MO 63110-0250.
Radiology. 2016 Mar;278(3):949-55. doi: 10.1148/radiol.2016141475.
A 30-year-old woman with polycystic ovarian syndrome who was undergoing hormone replacement therapy presented with a 6-month history of a nonproductive cough and a 1-day history of hemoptysis (approximately 20 mL). Intravenous contrast material-enhanced (100 mL of Omnipaque 350; GE Healthcare, Princeton, NJ) computed tomographic (CT) pulmonary angiography was performed to evaluate for pulmonary embolism. On the basis of the CT pulmonary angiographic findings, chromogranin A and 5-hydroxyindoleacetic acid levels were measured and were 7 nmol/L (343 µg/L) (high) and 2.9 mg per 24 hours (15.167 µmol/d) (normal), respectively. This patient underwent bronchoscopy and biopsy. After these tests, she was referred for whole-body scintigraphy, which revealed an unexpected finding that was further investigated with fluorine 18 ((18)F) flurodeoxyglucose (FDG) positron emission tomography (PET) and CT.
一位 30 岁患有多囊卵巢综合征的女性正在接受激素替代疗法,她因非生产性咳嗽就诊,病史 6 个月,且 1 天前出现咯血(约 20 毫升)。为了评估是否存在肺栓塞,对其进行了静脉内对比增强(100 毫升欧乃派克 350;通用电气医疗,普林斯顿,新泽西州)计算机断层扫描(CT)肺动脉造影。基于 CT 肺动脉造影结果,测定嗜铬粒蛋白 A 和 5-羟吲哚乙酸水平,分别为 7 nmol/L(343 µg/L)(高)和 2.9 毫克/24 小时(15.167 µmol/d)(正常)。该患者接受了支气管镜检查和活检。这些检查后,她被转介进行全身闪烁扫描,结果显示出一个意外发现,进一步用氟 18(18)F 氟脱氧葡萄糖(FDG)正电子发射断层扫描(PET)和 CT 进行了调查。