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腹膜后腹腔镜治疗副神经节瘤:单中心经验

Retroperitoneal Laparoscopic Management of Paraganglioma: A Single Institute Experience.

作者信息

Xu Weifeng, Li Hanzhong, Ji Zhigang, Yan Weigang, Zhang Yushi, Zhang Xuebin, Li Qian

机构信息

Department of Urology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, 100730, China.

Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.

出版信息

PLoS One. 2016 Feb 17;11(2):e0149433. doi: 10.1371/journal.pone.0149433. eCollection 2016.

Abstract

OBJECTIVES

To explore the feasibility and safety of retroperitoneal laparoscopic resection of paraganglioma (RLPG) in a large study population.

METHODS

In a six-year period, 49 patients with primary retroperitoneal paragangliomas (PG) underwent retroperitoneal laparoscopic surgery in a single center. Medical records were reviewed, and collected the following data, which were clinical characteristics, perioperative data (operative time, estimated blood loss, intraoperative hemodynamic changes, intraoperative and postoperative complications, and open conversions), and follow-up data (recurrence or distant metastases).

RESULTS

All PGs were removed with negative tumor margin confirmed by postoperative histopathology. The operative time of RLPG was 101.59±31.12 minutes, and the estimated blood loss was 169.78±176.70ml. Intraoperative hypertensive and hypotensive episodes occurred in 25 cases and 27 cases, respectively. Two open conversions occurred. Two intraoperative complications occurred but were successfully managed endoscopically. Postoperative complications were minor and unremarkable. No local recurrence or distant metastasis were observed during the follow-up period.

CONCLUSIONS

Our experience indicates the feasibility and safety of resection of PGs in a relatively large study population.

摘要

目的

在一个大型研究人群中探讨腹膜后腹腔镜下副神经节瘤切除术(RLPG)的可行性和安全性。

方法

在六年期间,49例原发性腹膜后副神经节瘤(PG)患者在单一中心接受了腹膜后腹腔镜手术。回顾病历,并收集以下数据,包括临床特征、围手术期数据(手术时间、估计失血量、术中血流动力学变化、术中和术后并发症以及中转开腹情况)以及随访数据(复发或远处转移)。

结果

所有PG均被切除,术后组织病理学证实切缘阴性。RLPG的手术时间为101.59±31.12分钟,估计失血量为169.78±176.70ml。术中分别有25例和27例出现高血压和低血压发作。发生了2例中转开腹。发生了2例术中并发症,但通过内镜成功处理。术后并发症轻微且不显著。随访期间未观察到局部复发或远处转移。

结论

我们的经验表明在相对大型的研究人群中切除PG具有可行性和安全性。

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