Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.
Clinics (Sao Paulo). 2012;67 Suppl 1(Suppl 1):161-7. doi: 10.6061/clinics/2012(sup01)27.
Since the first laparoscopic adrenalectomy, the technique has evolved and it has become the standard of care for many adrenal diseases, including pheochromocytoma. Two laparoscopic accesses to the adrenal have been developed: transperitoneal and retroperitoneal. Retroperitoneoscopic adrenalectomy may be recommended for the treatment of pheochromocytoma with the same peri-operative outcomes of the transperitoneal approach because it allows direct access to the adrenal glands without increasing the operative risks. Although technically more demanding than the transperitoneal approach, retroperitoneoscopy can shorten the mean operative time, which is critical for cases with pheochromocytoma where minimizing the potential for intra-operative hemodynamic changes is essential. Blood loss and the convalescence time can be also shortened by this approach. There is no absolute indication for either the transperitoneal or retroperitoneal approach; however, the latter procedure may be the best option for patients who have undergone previous abdominal surgery and obese patients. Also, retroperitoneoscopic adrenalectomy is a good alternative for treating cases with inherited pheochromocytomas, such as multiple endocrine neoplasia type 2A, in which the pheochromocytoma is highly prevalent and frequently occurs bilaterally.
自从首例腹腔镜肾上腺切除术以来,该技术不断发展,现已成为许多肾上腺疾病(包括嗜铬细胞瘤)的治疗标准。目前已经开发出两种腹腔镜进入肾上腺的方法:经腹腔和腹膜后。对于嗜铬细胞瘤的治疗,后腹腔镜肾上腺切除术可能被推荐采用,因为它可以直接进入肾上腺,而不会增加手术风险,其围手术期结果与经腹腔方法相同。尽管在技术上比经腹腔方法要求更高,但后腹腔镜手术可以缩短平均手术时间,这对于嗜铬细胞瘤病例非常关键,因为必须尽量减少术中血流动力学变化的潜在风险。这种方法还可以减少出血量和康复时间。对于经腹腔或腹膜后方法,没有绝对的适应证;但是,对于既往腹部手术和肥胖患者,后者可能是最佳选择。此外,对于多发性内分泌肿瘤 2A 等遗传性嗜铬细胞瘤,后腹腔镜肾上腺切除术是一种很好的替代治疗方法,因为此类患者的嗜铬细胞瘤非常普遍,且常为双侧发生。