Suppr超能文献

[一名患有严重乳糜泻的6岁男孩的溃疡性结肠炎——病例报告]

[Ulcerative colitis in a 6-year-old boy with severe coeliac disease - a case report].

作者信息

Pawłowska-Kamieniak Agnieszka, Krawiec Paulina, Pac-Kożuchowska Elżbieta, Mroczkowska-Juchkiewcz Agnieszka, Kominek Katarzyna

机构信息

Department of Paediatrics, Medical University of Lublin.

出版信息

Pol Merkur Lekarski. 2016 Jan;40(235):21-4.

Abstract

Coeliac disease is a chronic immune-mediated inflammation of the small intestine elicited by the gluten ingestion in genetically susceptible people. In coeliac patients there is higher incidence of other autoimmune disorders like type 1 diabetes or Hashimoto's thyroiditis. The coexistence of coeliac disease and inflammatory bowel disease is rare. The spectrum of presentation of coeliac disease and inflammatory bowel disease may be similar. However, those disorders require various therapeutic approaches. Thus, early recognition of the overlap between coeliac disease and inflammatory bowel disease is crucial to apply appropriate treatment and to prevent possible complications. We report a case of a 6-year-old boy with a delay in physical and psychomotor development, rickets, severe anaemia and bloody diarrhoea. He was diagnosed with coeliac disease and ulcerative disease. The coexistence of both disorders is extremely rare in childhood. However, ulcerative colitis should be considered in coeliac children on restrictive gluten-free diet with persistent diarrhoea or bleeding from lower gastrointestinal tract. Screening for coeliac disease should be considered in children with ulcerative colitis with impaired physical development and lack of remission despite of proper treatment.

摘要

乳糜泻是一种由遗传易感人群摄入麸质引发的小肠慢性免疫介导性炎症。乳糜泻患者患其他自身免疫性疾病(如1型糖尿病或桥本甲状腺炎)的几率更高。乳糜泻与炎症性肠病同时存在的情况较为罕见。乳糜泻和炎症性肠病的临床表现可能相似。然而,这些疾病需要不同的治疗方法。因此,早期识别乳糜泻和炎症性肠病之间的重叠对于采取适当治疗和预防可能的并发症至关重要。我们报告一例6岁男孩,有身体和精神运动发育迟缓、佝偻病、严重贫血和血性腹泻。他被诊断为乳糜泻和溃疡性疾病。这两种疾病在儿童期同时存在极为罕见。然而,对于采用严格无麸质饮食但仍持续腹泻或下消化道出血的乳糜泻儿童,应考虑溃疡性结肠炎的可能。对于身体发育受损且尽管接受了适当治疗仍未缓解的溃疡性结肠炎儿童,应考虑进行乳糜泻筛查。

相似文献

3
Prevalence of inflammatory bowel disease among coeliac disease patients in a Hungarian coeliac centre.
BMC Gastroenterol. 2015 Oct 19;15:141. doi: 10.1186/s12876-015-0370-7.
5
Simultaneous presentation of coeliac disease and ulcerative colitis in a child.
J Paediatr Child Health. 1999 Apr;35(2):204-6. doi: 10.1046/j.1440-1754.1999.t01-1-00328.x.
6
Co-existing coeliac and inflammatory bowel disease in a patient with Turner's syndrome.
Aust N Z J Med. 1979 Jun;9(3):316-7. doi: 10.1111/j.1445-5994.1979.tb04148.x.
8
Co-occurrence of celiac disease and ulcerative colitis in a 12-year-old girl.
Fetal Pediatr Pathol. 2015 Apr;34(2):99-102. doi: 10.3109/15513815.2014.970262. Epub 2014 Oct 29.
9
Coeliac proctitis.
Scand J Gastroenterol. 1987 May;22(4):471-7. doi: 10.3109/00365528708991493.
10

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验