Akers Michael J
Int J Pharm Compd. 2015 Nov-Dec;19(6):471-6.
The achievement of a high-quality lyophilized (freeze-dried) dosage form involves the combination of optimal formulation design and optimal freeze-dry cycle design. This 2-part article describes how this can be done. Part 1 discusses the basic principles and procedures of lyophilization up to a discussion on the different stages of lyophilization. The stages of lyophilization are discussed in part 2.
高质量冻干剂型的实现涉及到优化配方设计和优化冻干周期设计的结合。这篇分两部分的文章描述了如何做到这一点。第一部分讨论了冻干的基本原理和程序，直至对冻干的不同阶段进行讨论。冻干阶段将在第二部分进行讨论。
