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股骨假体周围骨密度降低:一项使用双能X线吸收法对股骨头缺血性坏死与原发性骨关节炎患者行非骨水泥型全髋关节置换术后的对比研究。

Decreased femoral periprosthetic bone mineral density: a comparative study using DXA in patients after cementless total hip arthroplasty with osteonecrosis of the femoral head versus primary osteoarthritis.

作者信息

Craiovan Benjamin, Woerner Michael, Winkler Sebastian, Springorum Hans-Robert, Grifka Joachim, Renkawitz Tobias, Keshmiri Armin

机构信息

Department of Orthopedic Surgery, Regensburg University Medical Center, Kaiser-Karl-V-Allee 3, 93077, Bad Abbach, Germany.

出版信息

Arch Orthop Trauma Surg. 2016 May;136(5):709-13. doi: 10.1007/s00402-016-2423-y. Epub 2016 Feb 18.

Abstract

INTRODUCTION

Trabecular properties in osteonecrosis of the femoral head (ONFH) are altered for bone volume and structure in the femoral head and proximal femoral canal. We analysed the periprosthetic bone mineral density (BMD) as a correlate to bony ingrowth in patients with ONFH who received a cementless THA.

MATERIALS AND METHODS

We performed a matched-pair analysis of 100 patients with ONFH (n = 50) and primary osteoarthritis (n = 50) who received the same, unilateral cementless THA. We compared the periprosthetic BMD 5 years after surgery by means of dual energy X-ray absorptiometry (DXA) analysing the seven femoral regions of interest (ROIs) according to Gruen.

RESULTS

Within the ONFH group, significantly lower BMD values were found in the ROI 1 and 7 (p < 0.05). No statistically significant difference was found for ROIs 2-6.

CONCLUSIONS

An altered periprosthetic bone stock in the proximal femur in patients with prior ONFH might be a possible risk factor for premature loosening of the femoral stem in THA. Surgeons need to consider coating and fixation philosophy of cementless implants when choosing the right stem for patients with ONFH.

摘要

引言

股骨头坏死(ONFH)患者的小梁骨特性在股骨头和股骨近端管的骨体积和结构方面发生了改变。我们分析了接受非骨水泥型全髋关节置换术(THA)的ONFH患者的假体周围骨密度(BMD),作为与骨长入相关的指标。

材料与方法

我们对100例接受相同单侧非骨水泥型THA的患者进行了配对分析,其中ONFH患者50例,原发性骨关节炎患者50例。术后5年,我们通过双能X线吸收法(DXA)比较假体周围骨密度,根据Gruen分析法分析七个感兴趣的股骨区域(ROI)。

结果

在ONFH组中,ROI 1和7的骨密度值显著较低(p < 0.05)。ROI 2 - 6未发现统计学上的显著差异。

结论

既往有ONFH的患者股骨近端假体周围骨储备改变可能是THA中股骨柄过早松动的一个潜在危险因素。外科医生在为ONFH患者选择合适的股骨柄时,需要考虑非骨水泥型植入物的涂层和固定理念。

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