Academic Department of Vascular Surgery, King's College London, St. Thomas' Hospital, London SE1 7EH, UK.
Department of Thrombosis and Haemostasis, Guy's and St. Thomas' Hospitals, NHS Foundation Trust, London SE1 7EH, UK.
Br Med Bull. 2016 Mar;117(1):107-20. doi: 10.1093/bmb/ldw006. Epub 2016 Feb 17.
This review aims to provide an update on the management of deep vein thrombosis (DVT).
A systematic search of PubMed, Google Scholar and Cochrane databases was carried out.
Direct oral anticoagulants (DOACs) are as effective and easier to use than vitamin K antagonists for the treatment of DVT. Catheter-directed thrombolysis can reduce post thrombotic syndrome in patients with iliofemoral DVT. Compression bandaging can help heal a venous ulcer.
Compression hosiery to prevent post thrombotic syndrome. Long-term evidence to show clinical benefit of using endovenous therapies to restore deep vein patency.
Developing imaging methods to identify patients who would benefit from venous thrombolysis. The evolution of dedicated venous stents.
Understanding the mechanisms that lead to stent occlusion and investigation into the appropriate treatments that could prevent in-stent thrombosis is required.
本篇综述旨在提供深静脉血栓形成（DVT）治疗的最新进展。
系统检索了 PubMed、Google Scholar 和 Cochrane 数据库。
与维生素 K 拮抗剂相比，直接口服抗凝剂（DOACs）在治疗 DVT 方面同样有效且更易于使用。导管定向溶栓可降低髂股 DVT 患者的血栓后综合征发生率。加压包扎有助于治疗静脉溃疡。
加压袜是否有助于预防血栓后综合征。静脉内治疗恢复深静脉通畅以显示临床获益的长期证据。
开发可识别适合静脉溶栓患者的影像学方法。专用静脉支架的发展。
需要了解导致支架阻塞的机制，并研究可预防支架内血栓形成的适当治疗方法。
