Bremel R D, Yom H C, Bleck G T
Department of Dairy Science, University of Wisconsin, Madison 53706.
J Dairy Sci. 1989 Oct;72(10):2826-33. doi: 10.3168/jds.S0022-0302(89)79428-5.
Advances in genetic technology have made it possible to consider making substantial changes either in the composition of milk or in the production of entirely new products in milk. The technological capabilities that have given rise to the introduction and expression of new genes in animals are discussed. Examples are given of transgenic animals that express foreign proteins in their milk. Advantages of the mammary synthesis of proteins are discussed and potential alterations of milk composition and scenarios for introduction of new proteins are considered. Technological capabilities that either currently exist or are being developed are discussed along with the requirements for making it feasible to utilize the technology on a broad scale in dairy cattle.
基因技术的进步使得对牛奶成分进行重大改变或生产全新的牛奶产品成为可能。本文讨论了促使在动物体内引入和表达新基因的技术能力。文中给出了在乳汁中表达外源蛋白的转基因动物实例。探讨了乳腺合成蛋白质的优势，并考虑了牛奶成分的潜在改变以及引入新蛋白质的设想。文中还讨论了目前已存在或正在研发的技术能力，以及在奶牛中广泛应用该技术所需满足的条件。
