Chun Jae Min, Lim Kyoung Hoon
Department of Surgery, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, 130 Dongduk-ro, Jung-gu, Daegu, 700-721, South Korea.
Department of Surgery, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, 130 Dongduk-ro, Jung-gu, Daegu, 700-721, South Korea.
Int J Surg Case Rep. 2016;21:20-2. doi: 10.1016/j.ijscr.2016.02.010. Epub 2016 Feb 8.
Gastrointestinal stromal tumors (GISTs) of the appendix are extremely rare. To date, only 15 cases have been reported in the English literature. Here, we present a new case of an appendiceal GIST with appendicitis.
A 68-year-old man who complained of right lower abdominal tenderness underwent surgery for a cystic mass mimicking Meckel's diverticulum. Laparoscopy revealed a mass protruding from the proximal appendix with distal appendicitis. Complete resection with adequate margins was performed. Histology showed a spindle cell GIST without mitotic activity as well as a strong expression of CD117 and CD34.
Primary appendiceal GIST occur at a very low rate and their symptoms are nonspecific. Accordingly, rare tumors of appendix including GISTs should be considered in the differential diagnosis of atypical symptoms or image findings.
阑尾胃肠道间质瘤(GIST)极为罕见。迄今为止,英文文献中仅报道了15例。在此,我们报告一例合并阑尾炎的阑尾GIST新病例。
一名68岁男性,因右下腹部压痛就诊,接受手术治疗,术中发现一个类似梅克尔憩室的囊性肿物。腹腔镜检查显示肿物从阑尾近端突出,伴有远端阑尾炎。进行了完整切除且切缘足够。组织学检查显示为无有丝分裂活性的梭形细胞GIST,CD117和CD34呈强阳性表达。
原发性阑尾GIST发病率极低,症状无特异性。因此,在非典型症状或影像学表现的鉴别诊断中应考虑包括GIST在内的罕见阑尾肿瘤。