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模仿梅克尔憩室的阑尾胃肠道间质瘤:病例报告并文献复习

Gastrointestinal stromal tumor of the vermiform appendix mimicking Meckel's diverticulum: Case report with literature review.

作者信息

Chun Jae Min, Lim Kyoung Hoon

机构信息

Department of Surgery, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, 130 Dongduk-ro, Jung-gu, Daegu, 700-721, South Korea.

Department of Surgery, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, 130 Dongduk-ro, Jung-gu, Daegu, 700-721, South Korea.

出版信息

Int J Surg Case Rep. 2016;21:20-2. doi: 10.1016/j.ijscr.2016.02.010. Epub 2016 Feb 8.

Abstract

INTRODUCTION

Gastrointestinal stromal tumors (GISTs) of the appendix are extremely rare. To date, only 15 cases have been reported in the English literature. Here, we present a new case of an appendiceal GIST with appendicitis.

PRESENTATION OF CASE

A 68-year-old man who complained of right lower abdominal tenderness underwent surgery for a cystic mass mimicking Meckel's diverticulum. Laparoscopy revealed a mass protruding from the proximal appendix with distal appendicitis. Complete resection with adequate margins was performed. Histology showed a spindle cell GIST without mitotic activity as well as a strong expression of CD117 and CD34.

CONCLUSION

Primary appendiceal GIST occur at a very low rate and their symptoms are nonspecific. Accordingly, rare tumors of appendix including GISTs should be considered in the differential diagnosis of atypical symptoms or image findings.

摘要

引言

阑尾胃肠道间质瘤(GIST)极为罕见。迄今为止,英文文献中仅报道了15例。在此,我们报告一例合并阑尾炎的阑尾GIST新病例。

病例介绍

一名68岁男性,因右下腹部压痛就诊,接受手术治疗,术中发现一个类似梅克尔憩室的囊性肿物。腹腔镜检查显示肿物从阑尾近端突出,伴有远端阑尾炎。进行了完整切除且切缘足够。组织学检查显示为无有丝分裂活性的梭形细胞GIST,CD117和CD34呈强阳性表达。

结论

原发性阑尾GIST发病率极低,症状无特异性。因此,在非典型症状或影像学表现的鉴别诊断中应考虑包括GIST在内的罕见阑尾肿瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92f7/4802133/03b375271d41/gr1.jpg

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