Yasuda T, Suzuki R, Okitsu T, Asai Y, Matsushima A, Takizawa K
Kansenshogaku Zasshi. 1989 Nov;63(11):1281-6. doi: 10.11150/kansenshogakuzasshi1970.63.1281.
Distribution of the c protein fractions of group B streptococci and relation to heat-labile antigens for agglutination were investigated. The results were summarized as follows: 1. Analysis of antigenicity of the c protein in group B streptococcal strains isolated revealed that 74% of the type Ia/c strains carried only alpha antigen, and 76% of the type Ib/c strains contained both alpha and beta antigens. Component of the c protein fractions in most of type Ia/c strains isolated was different from that in reference strains. 2. Of 37 Ia/c alpha strains, 45.9% were determined non-typable, 32.4% were Ia/W, 13.5% were Ia/S, and 8.1% were Ia/Q in the agglutination for heat-labile antigens. Of 8 Ia/c alpha beta strains, 87.5% were Ia/Q, and 12.5% were Ia/SW. Of 5 Ia/c beta strains, 60% were Ia/Q, and 40% were Ia/QW. Of 19 Ib/c alpha beta strains, 68.4% were Ib/-, and 31.6% were Ib/S. Of 5 Ib/c alpha strains, 60% were Ib/-, and 40% were Ib/S. One Ib/c beta strain was Ib/-. 3. Because trypsin-sensitive portions of the beta antigens were lost, preparation of antigens for agglutination by pancreatic digestion could not exactly reflect results of the precipitation method.
对B族链球菌c蛋白组分的分布及其与热不稳定凝集抗原的关系进行了研究。结果总结如下：1. 对分离出的B族链球菌菌株中c蛋白的抗原性分析表明，74%的Ia/c型菌株仅携带α抗原，76%的Ib/c型菌株同时含有α和β抗原。大多数分离出的Ia/c型菌株中c蛋白组分与参考菌株不同。2. 在37株Ia/cα菌株中，45.9%在热不稳定抗原凝集试验中被判定为不可分型，32.4%为Ia/W型，13.5%为Ia/S型，8.1%为Ia/Q型。在8株Ia/cαβ菌株中，87.5%为Ia/Q型，12.5%为Ia/SW型。在5株Ia/cβ菌株中，60%为Ia/Q型，40%为Ia/QW型。在19株Ib/cαβ菌株中，68.4%为Ib/-型，31.6%为Ib/S型。在5株Ib/cα菌株中，60%为Ib/-型，40%为Ib/S型。1株Ib/cβ菌株为Ib/-型。3. 由于β抗原的胰蛋白酶敏感部分丢失，通过胰酶消化制备凝集抗原不能准确反映沉淀法的结果。
