胰腺疾病外科治疗的进展

Advances in Surgical Management of Pancreatic Diseases.

作者信息

Datta Jashodeep, Vollmer Charles M

机构信息

Division of Gastrointestinal Surgery, Department of Surgery, University of Pennsylvania Perelman School of Medicine, 3400 Spruce Street, Philadelphia, PA 19104, USA.

出版信息

Gastroenterol Clin North Am. 2016 Mar;45(1):129-44. doi: 10.1016/j.gtc.2015.10.002.

DOI:10.1016/j.gtc.2015.10.002

PMID:26895685

Abstract

The surgical management of pancreatic diseases is rapidly evolving, encompassing advances in evidence-driven selection of patients amenable for surgical therapy, preoperative risk stratification, refinements in the technical conduct of pancreatic operations, and quantification of postoperative morbidity. These advances have resulted in dramatic reductions in mortality following pancreatic surgery, particularly at high-volume pancreatic centers. Surgical decision making is complex, and requires an intimate understanding of disease pathobiology, host physiology, technical considerations, and evolving trends. This article highlights key developments in the contemporary surgical management of pancreatic diseases.

摘要

胰腺疾病的外科治疗正在迅速发展，涵盖了在循证选择适合手术治疗的患者、术前风险分层、胰腺手术技术操作的改进以及术后发病率量化等方面的进展。这些进展已使胰腺手术后的死亡率大幅降低，尤其是在大型胰腺疾病治疗中心。手术决策很复杂，需要深入了解疾病病理生物学、宿主生理学、技术考量以及不断变化的趋势。本文重点介绍了胰腺疾病当代外科治疗中的关键进展。