Diethorn M L, Weld L M
J Cardiovasc Nurs. 1989 Nov;4(1):1-10. doi: 10.1097/00005082-198911000-00002.
This article describes the interrelated processes and homeostatic controlling mechanisms of hemostasis and fibrinolysis. Hemostasis involves platelets, blood vessels, and coagulation proteins. Primary hemostasis is dependent on platelet adhesion, activation, secretion, and aggregation. Secondary hemostasis consists of intrinsic activation, extrinsic activation, and the common final pathway. Fibrinolysis results in clot dissolution and is initiated endogenously as plasminogen is converted to plasmin.
本文描述了止血和纤维蛋白溶解的相关过程及稳态控制机制。止血涉及血小板、血管和凝血蛋白。初级止血依赖于血小板的黏附、激活、分泌和聚集。次级止血包括内源性激活、外源性激活和共同的最终途径。纤维蛋白溶解导致血栓溶解,并随着纤溶酶原转化为纤溶酶而内源性启动。